Frailty and caregiver relationship quality in older patients diagnosed with transthyretin cardiac amyloidosis

被引：10

作者：

Fumagalli, Carlo ^{[1
,2
]}

Smorti, Martina ^{[3
]}

Ponti, Lucia ^{[4
,5
]}

Pozza, Francesca ^{[3
]}

Argiro, Alessia ^{[2
,5
]}

Credi, Giacomo ^{[2
]}

Di Mario, Carlo ^{[7
]}

Marfella, Raffaele ^{[1
]}

Marchionni, Niccolo ^{[8
]}

Olivotto, Iacopo ^{[2
,9
]}

Perfetto, Federico ^{[5
,6
]}

Ungar, Andrea ^{[10
]}

Cappelli, Francesco ^{[5
,7
]}

机构：

[1] Univ Campania Luigi Vanvitelli, Dept Adv Med & Surg Sci, Naples, Italy

[2] Careggi Univ Hosp, Cardiomyopathy Unit, Florence, Italy

[3] Univ Pisa, Dept Surg Med & Mol Pathol & Crit Care Med, Pisa, Italy

[4] Univ Urbino, Dept Humanities, I-61029 Urbino, Italy

[5] Careggi Univ Hosp, Tuscan Reg Amyloidosis Ctr, Florence, Italy

[6] Careggi Univ Hosp, Internal Med Div 4, Florence, Italy

[7] Careggi Univ Hosp, Cardiothoracovasc Dept, Div Intervent Struct Cardiol, Florence, Italy

[8] Univ Florence, Dept Expt & Clin Med, Florence, Italy

[9] Meyer Children Hosp, Florence, Italy

[10] Univ Florence, Geriatr Intens Care Unit, Florence, Italy

来源：

AGING CLINICAL AND EXPERIMENTAL RESEARCH | 2023年 / 35卷 / 06期

关键词：

ATTR-CA; Frailty; Caregiver; Quality of relationship; Depression; OF-LIFE; ADULTS;

D O I：

10.1007/s40520-023-02419-6

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Aim of the study was to explore frailty and quality of the relationship with the caregiver in a cohort of older patients with transthyretin cardiac amyloidosis (ATTR-CA). Sixty-eight consecutive ATTR-CA patients were recruited and assessed for frailty, depressive symptoms, quality of the relationship in terms of social support, or conflict toward caregivers, New York Heart Association Class (NYHA), and National Amyloid Center score (NAC Score) for grading disease severity. Results showed that 10% of patients were frail. Depressive symptoms were present in 46% of patients. Regression analyses showed that both mFI and depression were associated with worse perception of social support, and that mFI and NAC score were associated with higher levels of conflict perceived in the caregivers' relationship. Overall, the mFI score was associated with worse perceived social support and caregiver relationship quality. Tertiary care heart failure clinics should actively support the patient-caregiver relationship to improve quality of life.

引用

页码：1363 / 1367

页数：5