Association between cardiac conditions with venous leg ulcers in patients with chronic venous insufficiency

被引：6

作者：

Pizano, Alejandro ^{[1
]}

Bequeaith, Beau ^{[1
]}

Cifuentes, Sebastian ^{[2
]}

Figueroa, Valentin ^{[2
]}

Al Rustem, Haider ^{[1
]}

Ray, Hunter M. ^{[1
]}

Coogan, Sheila ^{[1
]}

Miller, Charles ^{[1
]}

Ulloa, Jorge H. ^{[2
]}

Harlin, Stuart A. ^{[1
]}

机构：

[1] Univ Texas Hlth Sci Ctr Houston, McGovern Med Sch, Dept Cardiothorac & Vasc Surg, 5323 Harry Hines,Fannin St, Houston, TX 77054 USA

[2] Univ Los Andes, Univ Hosp Fdn Santa Fe Bogota, Dept Vasc Surg, Bogota, Colombia

来源：

PHLEBOLOGY | 2023年 / 38卷 / 04期

关键词：

venous leg insufficiency; venous leg ulcers; heart failure; atrial fibrillation; pulmonary hypertension; right heart failure; RISK-FACTORS; EPIDEMIOLOGY;

D O I：

10.1177/02683555231162294

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Introduction Venous leg ulcers (VLUs) are the final stage of chronic venous insufficiency. This study aims to characterize the association between cardiovascular diseases and VLU. Methods A multicentric case-control study analyzed 17,788 patients between 2015 and 2020. Cases were matched (1:2) by age and sex, and odds ratios (OR) were analyzed with conditional logistic regressions adjusted by risk factors. Results The prevalence of VLU was 15.2%. 2390 cases were analyzed. Diseases found to be associated with VLU were atrial fibrillation (OR, 1.21; 95% CI: 1.03-1.42), pulmonary hypertension (OR, 1.45; 95% CI: 1.06-2.00), right heart failure (OR, 1.27; 95% CI: 1.13-1.43), peripheral artery disease (OR, 2.21; 95% CI: 1.90-2.56), and history of pulmonary embolism (OR, 1.45; 95% CI: 1.06-2.00). Conclusions Certain cardiovascular conditions showed an association with VLU. Further studies are warranted to evaluate the effect that treating concomitant cardiovascular diseases might exert on the natural history of venous leg ulcers.

引用

页码：281 / 286

页数：6