Polysaccharides, proteins, and synthetic polymers based multimodal hydrogels for various biomedical applications: A review

被引：51

作者：

Kumar, Anuj ^{[1
,2
]}

Sood, Ankur ^{[1
]}

Agrawal, Garima ^{[3
]}

Thakur, Sourbh ^{[4
]}

Thakur, Vijay Kumar ^{[5
,6
]}

Tanaka, Masaru ^{[7
]}

Mishra, Yogendra Kumar ^{[8
]}

Christie, Graham ^{[9
]}

Mostafavi, Ebrahim ^{[10
]}

Boukherroub, Rabah ^{[11
]}

Hutmacher, Dietmar W. ^{[12
,13
,14
,15
]}

Han, Sung Soo ^{[1
]}

机构：

[1] Yeungnam Univ, Sch Chem Engn, 280 Daehak Ro, Gyongsan 38541, South Korea

[2] Indian Inst Technol BHU, Sch Mat Sci & Technol, Varanasi 221005, Uttar Pradesh, India

[3] Indian Inst Technol Mandi, Adv Mat Res Ctr, Sch Chem Sci, Kamand 175075, Himachal Prades, India

[4] Silesian Tech Univ, Dept Organ Chem Bioorgan Chem & Biotechnol, B Krzywoustego 4, PL-44100 Gliwice, Poland

[5] SRUC, Biorefining & Adv Mat Res Ctr, Barony Campus, Dumfries DG1 3NE, Scotland

[6] Univ Petr & Energy Studies UPES, Sch Engn, Dehra Dun 248007, Uttaranchal, India

[7] Kyushu Univ, Inst Mat Chem & Engn, 744 Motooka Nishi Ku, Fukuoka 8190395, Japan

[8] Univ Southern Denmark, Mads Clausen Inst, Smart Mat, Alsion 2, DK-6400 Sonderborg, Denmark

[9] Univ Cambridge, Dept Chem Engn & Biotechnol, Cambridge CB3 0AS, England

[10] Stanford Univ, Dept Med, Sch Med, Stanford, CA 94305 USA

[11] Univ Lille, Univ Polytech Hauts Defrance, CNRS, UMR 8520 IEMN, F-59000 Lille, France

[12] Queensland Univ Technol, Max Planck Queensland Ctr MPQC Mat Sci Extracellul, Brisbane, Qld 4000, Australia

[13] Queensland Univ Technol, Ctr Biomed Technol, Sch Mech Med & Proc Engn, Brisbane, Qld 4000, Australia

[14] Queensland Univ Technol, ARC Training Ctr Cell & Tissue Engn Technol, Brisbane, Qld 4000, Australia

[15] Queensland Univ Technol, Australian Res Council ARC Training Ctr Multiscale, Brisbane, Qld 4000, Australia

来源：

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES | 2023年 / 247卷

基金：

新加坡国家研究基金会;

关键词：

Biomaterials; Polysaccharides; Hydrogels; MUSSEL-INSPIRED ADHESIVE; SELF-HEALING HYDROGEL; STEM-CELLS; TISSUE-ADHESIVE; NANOCOMPOSITE HYDROGEL; STRAIN SENSORS; ZWITTERIONIC HYDROGELS; ANTIBACTERIAL ACTIVITY; MECHANICAL-PROPERTIES; BLOOD COMPATIBILITY;

D O I：

10.1016/j.ijbiomac.2023.125606

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nature-derived or biologically encouraged hydrogels have attracted considerable interest in numerous biomedical applications owing to their multidimensional utility and effectiveness. The internal architecture of a hydrogel network, the chemistry of the raw materials involved, interaction across the interface of counter ions, and the ability to mimic the extracellular matrix (ECM) govern the clinical efficacy of the designed hydrogels. This review focuses on the mechanistic viewpoint of different biologically driven/inspired biomacromolecules that encourages the architectural development of hydrogel networks. In addition, the advantage of hydrogels by mimicking the ECM and the significance of the raw material selection as an indicator of bioinertness is deeply elaborated in the review. Furthermore, the article reviews and describes the application of polysaccharides, proteins, and synthetic polymer-based multimodal hydrogels inspired by or derived from nature in different biomedical areas. The review discusses the challenges and opportunities in biomaterials along with future prospects in terms of their applications in biodevices or functional components for human health issues. This review provides information on the strategy and inspiration from nature that can be used to develop a link between multimodal hydrogels as the main frame and its utility in biomedical applications as the primary target.

引用

页数：31

共 286 条

[1] Identification and Analysis of Key Parameters for the Ossification on Particle Functionalized Composites Hydrogel Materials [J].