Fluorescent and Biocompatible Nitrogen and Sulfur Co-Doped Carbon Nanodot as an Ocular Fundus Angiography Imaging Agent

被引：4

作者：

Ilhan, Hasan ^{[1
]}

Erdem, Burak ^{[2
]}

Ozkasapoglu, Sezgin ^{[3
]}

Yayla, Muhammed ^{[4
]}

Bas, Orhan ^{[5
]}

Celikkan, Huseyin ^{[6
]}

机构：

[1] Ordu Univ, Fac Sci, Dept Chem, TR-52200 Ordu, Turkiye

[2] Ordu Univ, Fac Med, Dept Ophthalmol, TR-52200 Ordu, Turkiye

[3] Turkish Energy Nucl & Mineral Res Agcy, Boron Res Inst TENMAK BOREN, TR-06530 Ankara, Turkiye

[4] Kafkas Univ, Fac Med, Dept Pharmacol, TR-36100 Kars, Turkiye

[5] Samsun Univ, Fac Med, Dept Anat, TR-55080 Samsun, Turkiye

[6] Gazi Univ, Fac Sci, Dept Chem, TR-06560 Ankara, Turkiye

来源：

JOURNAL OF FLUORESCENCE | 2023年 / 33卷 / 05期

关键词：

Carbon nanodots; Fluorescence imaging; Fundus angiography; GREEN SYNTHESIS; DOTS;

D O I：

10.1007/s10895-023-03200-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The florescence characteristics and the toxicities of carbon nanodots (CDs) are directly related to their elemental compositions. Fluorescent and non-toxic agent for imaging of biological systems was aimed. Sulfur and nitrogen co-doped CDs (S/N-CDs) was hydrothermally produced in an average size of 8 nm. S/N-CDs showed blue fluorescence under UV-light with an excitation wavelength of 365 nm. After 24 h, S/N-CDs was non-cytotoxic in HUVEC and L929 cells. S/N-CDs have a great potential to act as an alternative material for commercial fluorescent materials with its 85.5% of quantum yield. S/N-CDs was approved in vitro as an imaging agent for an ocular fundus angiography of rats.

引用

页码：1917 / 1925

页数：9

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[2] Correction to: Fluorescent and Biocompatible Nitrogen and Sulfur Co-Doped Carbon Nanodot as an Ocular Fundus Angiography Imaging Agent
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