Advances of Antimicrobial Peptide-Based Biomaterials for the Treatment of Bacterial Infections

被引：105
作者：
Li, Guoyu [1 ]
Lai, Zhenheng [1 ]
Shan, Anshan [1 ]
机构：
[1] Northeast Agr Univ, Inst Anim Nutr, Harbin 150030, Peoples R China
来源：
ADVANCED SCIENCE | 2023年 / 10卷 / 11期
基金：
中国国家自然科学基金;
关键词：
antimicrobial peptides; bacterial infection; biomaterial delivery; design strategy; mouse models; treatment potential; ANTIBACTERIAL ACTIVITY; GOLD NANOPARTICLES; HUMAN LACTOFERRIN; HOST-DEFENSE; MOUSE MODEL; IN-VITRO; DESIGN; SELECTIVITY; GENTAMICIN; PLECTASIN;
D O I：
10.1002/advs.202206602
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Owing to the increase in multidrug-resistant bacterial isolates in hospitals globally and the lack of truly effective antimicrobial agents, antibiotic resistant bacterial infections have increased substantially. There is thus an urgent need to develop new antimicrobial drugs and their related formulations. In recent years, natural antimicrobial peptides (AMPs), AMP optimization, self-assembled AMPs, AMP hydrogels, and biomaterial-assisted delivery of AMPs have shown great potential in the treatment of bacterial infections. In this review, it is focused on the development prospects and shortcomings of various AMP-based biomaterials for treating animal model infections, such as abdominal, skin, and eye infections. It is hoped that this review will inspire further innovations in the design of AMP-based biomaterials for the treatment of bacterial infections and accelerate their commercialization.
引用
收藏
页数：23
相关论文
共 188 条
  • [41] Gram-selective antibacterial peptide hydrogels
    Hou, Yangqian
    Tan, Tingyuan
    Guo, Zhen
    Ji, Yuwen
    Hu, Jun
    Zhang, Yi
    [J]. BIOMATERIALS SCIENCE, 2022, 10 (14) : 3831 - 3844
  • [42] Isolation and characterization of an antimicrobial peptide from bovine hemoglobin α-subunit
    Hu, Jianhe
    Xu, Minglu
    Hang, Bolin
    Wang, Lan
    Wang, Qing
    Chen, Junjie
    Song, Tao
    Fu, Dengfeng
    Wang, Ziliang
    Wang, Sanhu
    Liu, Xingyou
    [J]. WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2011, 27 (04) : 767 - 771
  • [43] Antimicrobial peptides/ciprofloxacin-loaded O-carboxymethyl chitosan/self-assembling peptides hydrogel dressing with sustained-release effect for enhanced anti-bacterial infection and wound healing
    Huan, Yuchen
    Kong, Qing
    Tang, Qingjuan
    Wang, Yuming
    Mou, Haijin
    Ying, Rui
    Li, Chunjun
    [J]. CARBOHYDRATE POLYMERS, 2022, 280
  • [44] RETRACTED: Use of the Antimicrobial Peptide Pardaxin (GE33) To Protect against Methicillin-Resistant Staphylococcus aureus Infection in Mice with Skin Injuries (Retracted Article)
    Huang, Han-Ning
    Pan, Chieh-Yu
    Chan, Yi-Lin
    Chen, Jyh-Yih
    Wu, Chang-Jer
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 58 (03) : 1538 - 1545
  • [45] Peptide hormones and lipopeptides: from self-assembly to therapeutic applications
    Hutchinson, J. A.
    Burholt, S.
    Hamley, I. W.
    [J]. JOURNAL OF PEPTIDE SCIENCE, 2017, 23 (02) : 82 - 94
  • [46] Novel approaches for the treatment of infections due to multidrug-resistant bacterial pathogens
    Imran, Mohmmad
    Ahmad, Mohammad Naiyaz
    Dasgupta, Arunava
    Rana, Preeti
    Srinivas, Nanduri
    Chopra, Sidharth
    [J]. FUTURE MEDICINAL CHEMISTRY, 2022, 14 (15) : 1133 - 1148
  • [47] Conformational Stability Study of a Therapeutic Peptide Plectasin Using Molecular Dynamics Simulations in Combination with NMR
    Indrakumar, Sowmya
    Zalar, Matja
    Pohl, Christin
    Norgaard, Allan
    Streicher, Werner
    Harris, Pernille
    Golovanov, Alexander P.
    Peters, Gunther H. J.
    [J]. JOURNAL OF PHYSICAL CHEMISTRY B, 2019, 123 (23) : 4867 - 4877
  • [48] Alternative Therapeutic Interventions: Antimicrobial Peptides and Small Molecules to Treat Microbial Keratitis
    Jadi, Praveen Kumar
    Sharma, Prerana
    Bhogapurapu, Bharathi
    Roy, Sanhita
    [J]. FRONTIERS IN CHEMISTRY, 2021, 9
  • [49] Nanomedicine and advanced technologies for burns: Preventing infection and facilitating wound healing
    Jahromi, Mirza Ali Mofazzal
    Zangabad, Parham Sahandi
    Basri, Seyed Masoud Moosavi
    Zangabad, Keyvan Sahandi
    Ghamarypour, Ameneh
    Aref, Amir R.
    Karimi, Mandi
    Hamblin, Michael R.
    [J]. ADVANCED DRUG DELIVERY REVIEWS, 2018, 123 : 33 - 64
  • [50] 2-stage revision of 120 deep infected hip and knee prostheses using gentamicin-PMMA beads Results after 5 (2-20) years
    Janssen, Daniel M. C.
    Geurts, Jan A. P.
    Jutten, Liesbeth M. C.
    Walenkamp, Geert H. I. M.
    [J]. ACTA ORTHOPAEDICA, 2016, 87 (04) : 324 - 332
12345678910