Sentinel Lymph Node Detection in Breast Cancer: An Innovative Technique

被引:1
|
作者
Izzo, Paolo [1 ]
De Intinis, Claudia [1 ]
Sibio, Simone [1 ]
Basso, Luigi [1 ]
Polistena, Andrea [1 ]
Gabriele, Raimondo [1 ]
Codacci-Pisanelli, Massimo [1 ]
Izzo, Luciano [1 ]
Izzo, Sara [2 ]
机构
[1] Rome Sapienza Univ Rome, Dept Surg Pietro Valdoni, Policlin Umberto I, I-00128 Rome, Italy
[2] Univ Campania Luigi Vanvitelli, Dept Med Surg Neurologic Metab & Ageing Sci, Unit Colorectal Surg, I-81100 Caserta, Italy
关键词
SLNB; SPIO; ALND; LS; superparamagnetic iron oxide nanoparticles; BIOPSY; FEASIBILITY;
D O I
10.3390/diagnostics13122030
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
(1) Background: Sentinel lymph node biopsy is important in the search for metastases, especially in patients with malignant breast disease. Our study proposed new techniques to prevent complications such as possible postoperative seroma formation, pain or hypoesthesia of the axillary cord and medial arm surface, as well as motor deficits, to avoid disabling outcomes and presents initial data from our experience with the sentinel lymph node biopsy technique. (2) Methods: We mainly used two radioactive tracer detection techniques and a new technique using a radiotracer called Sentimag-magtrace. The positive lymph node was located and removed to perform histologic analysis. In our study, we evaluate 100 patients who underwent breast cancer surgery. (3) Results: We calculated the identification rates of the different methods of sentinel lymph node detection and found that it was 88.9% using radioactive tracers vs. 89.5% using the magnetic tracer technology (Sentimag). (4) Conclusions: Thus, this technique avoids radiation exposure for both patients and health care providers, and can reduce costs and time.
引用
收藏
页数:12
相关论文
共 50 条
  • [31] Sentinel Lymph Node Biopsy in Breast Cancer. Principle, Difficulties and Pitfalls
    Iancu, George
    Mustata, Laura M.
    Cigaran, Ruxandra
    Gica, Nicolae
    Botezatu, Radu
    Median, Dragos
    Panaitescu, Anca Maria
    Peltecu, Gheorghe
    CHIRURGIA, 2021, 116 (05) : 533 - 541
  • [32] Incorporation of Sentinel Lymph Node Metastasis Size Into a Nomogram Predicting Nonsentinel Lymph Node Involvement in Breast Cancer Patients With a Positive Sentinel Lymph Node
    Mittendorf, Elizabeth A.
    Hunt, Kelly K.
    Boughey, Judy C.
    Bassett, Roland
    Degnim, Amy C.
    Harrell, Robyn
    Yi, Min
    Meric-Bernstam, Funda
    Ross, Merrick I.
    Babiera, Gildy V.
    Kuerer, Henry M.
    Hwang, Rosa F.
    ANNALS OF SURGERY, 2012, 255 (01) : 109 - 115
  • [33] Strategies in case of metastatic sentinel lymph node in breast cancer
    Costaz, Helene
    Rouffiac, Magali
    Boulle, Delphine
    Arnould, Laurent
    Beltjens, Francoise
    Desmoulins, Isabelle
    Peignaux, Karine
    Ladoire, Sylvain
    Vincent, Laura
    Jankowski, Clementine
    Coutant, Charles
    BULLETIN DU CANCER, 2020, 107 (06) : 672 - 685
  • [34] An innovative method for precise lymph node detection before surgical treatment in breast cancer
    Matovic, Milovan
    Nikolic, Dalibor
    Filipovic, Nenad
    Jeremic, Marija
    Jankovic, Slobodan M.
    Ninkovic, Srdjan
    Cvetkovic, Aleksandar
    Vlajkovic, Marina
    Rankovic, Ana
    HELLENIC JOURNAL OF NUCLEAR MEDICINE, 2017, 20 (02): : 141 - 145
  • [35] Axillary lymph node dissection in patients with breast cancer and sentinel lymph node micrometastasis or isolated tumor cells: is it necessary?
    Attene, Federico
    Paliogiannis, Panagiotis
    Scognamillo, Fabrizio
    Trignano, Emilio
    Pala, Carlo
    Trignano, Mario
    TUMORI JOURNAL, 2012, 98 (03): : 320 - 323
  • [36] Predicting sentinel lymph node metastasis in breast cancer with lymphoscintigraphy
    Noguchi, Atsushi
    Onoguchi, Masahisa
    Ohnishi, Takeshi
    Hashizume, Terumi
    Kajita, Akiyoshi
    Funauchi, Masahiro
    Katsuda, Toshizo
    Motomura, Kazuyoshi
    ANNALS OF NUCLEAR MEDICINE, 2011, 25 (03) : 221 - 226
  • [37] Sentinel Lymph Node Dissection in Locally Recurrent Breast Cancer
    Uth, Charlotte Caspara
    Christensen, Mette Haulund
    Oldenbourg, Mette Holmqvist
    Kjaer, Christina
    Garne, Jens Peter
    Teilum, Dorthe
    Kroman, Niels
    Tvedskov, Tove Filtenborg
    ANNALS OF SURGICAL ONCOLOGY, 2015, 22 (08) : 2526 - 2531
  • [38] The clinical significance of sentinel lymph node micrometastasis in breast cancer
    Patani, Neill
    Mokbel, Kefah
    BREAST CANCER RESEARCH AND TREATMENT, 2009, 114 (03) : 393 - 402
  • [39] The role of Micrometastatic Disease in Sentinel Lymph Node in Breast Cancer
    Rovera, Francesca
    Frattini, Francesco
    Chiappa, Corrado
    Piscopo, Cristiano
    Bianchi, Veronica
    Dionigi, Gianlorenzo
    Rausei, Stefano
    Boni, Luigi
    Dionigi, Renzo
    BREAST JOURNAL, 2010, 16 : S26 - S28
  • [40] Clinical significance of breast cancer micrometastasis in the sentinel lymph node
    Shimazu, Kenzo
    Noguchi, Shinzaburo
    SURGERY TODAY, 2016, 46 (02) : 155 - 160