Sentinel Lymph Node Detection in Breast Cancer: An Innovative Technique

被引:1
|
作者
Izzo, Paolo [1 ]
De Intinis, Claudia [1 ]
Sibio, Simone [1 ]
Basso, Luigi [1 ]
Polistena, Andrea [1 ]
Gabriele, Raimondo [1 ]
Codacci-Pisanelli, Massimo [1 ]
Izzo, Luciano [1 ]
Izzo, Sara [2 ]
机构
[1] Rome Sapienza Univ Rome, Dept Surg Pietro Valdoni, Policlin Umberto I, I-00128 Rome, Italy
[2] Univ Campania Luigi Vanvitelli, Dept Med Surg Neurologic Metab & Ageing Sci, Unit Colorectal Surg, I-81100 Caserta, Italy
关键词
SLNB; SPIO; ALND; LS; superparamagnetic iron oxide nanoparticles; BIOPSY; FEASIBILITY;
D O I
10.3390/diagnostics13122030
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
(1) Background: Sentinel lymph node biopsy is important in the search for metastases, especially in patients with malignant breast disease. Our study proposed new techniques to prevent complications such as possible postoperative seroma formation, pain or hypoesthesia of the axillary cord and medial arm surface, as well as motor deficits, to avoid disabling outcomes and presents initial data from our experience with the sentinel lymph node biopsy technique. (2) Methods: We mainly used two radioactive tracer detection techniques and a new technique using a radiotracer called Sentimag-magtrace. The positive lymph node was located and removed to perform histologic analysis. In our study, we evaluate 100 patients who underwent breast cancer surgery. (3) Results: We calculated the identification rates of the different methods of sentinel lymph node detection and found that it was 88.9% using radioactive tracers vs. 89.5% using the magnetic tracer technology (Sentimag). (4) Conclusions: Thus, this technique avoids radiation exposure for both patients and health care providers, and can reduce costs and time.
引用
收藏
页数:12
相关论文
共 50 条
  • [1] The Sentinel Lymph Node: a suitable technique in breast cancer treatment?
    Petronella, Pasquale
    Scorzelli, Marco
    Benevento, Raffaella
    Corbisiero, Maria Carmela
    Freda, Fulvio
    Canonico, Silvestro
    ANNALI ITALIANI DI CHIRURGIA, 2012, 83 (02) : 119 - 123
  • [2] Integrated Photoacoustic Pen for Breast Cancer Sentinel Lymph Node Detection
    Jiang, Daohuai
    Zhao, Jiaxian
    Zhang, Yifan
    Cong, Binbin
    Shen, Yuting
    Gao, Feng
    2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS), 2022,
  • [3] Classic and novel approaches to sentinel lymph node detection in patients with invasive breast cancer
    Klein, M.
    Badidova, J.
    Polak, S.
    Varga, I
    BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY, 2021, 122 (01): : 18 - 23
  • [4] Sentinel Lymph Node Technique in Endometrial Cancer
    Staley, Allison
    Sullivan, Stephanie A.
    Rossi, Emma C.
    OBSTETRICAL & GYNECOLOGICAL SURVEY, 2017, 72 (05) : 289 - 295
  • [5] Sentinel Lymph Node Methods in Breast Cancer
    Giammarile, Francesco
    Vidal-Sicart, Sergi
    Paez, Diana
    Pellet, Olivier
    Enrique, Estrada-Lobato
    Mikhail-Lette, Miriam
    Morozova, Olga
    Camila, Navarro Marulanda Maria
    Ivonne, Rodriguez Sanchez Diana
    Bolton, Roberto C. Delgado
    Olmos, Renato A. Valdes
    Mariani, Giuliano
    SEMINARS IN NUCLEAR MEDICINE, 2022, 52 (05) : 551 - 560
  • [6] Sentinel lymph node biopsy in breast cancer
    Luschin, Gero
    WIENER MEDIZINISCHE WOCHENSCHRIFT, 2010, 160 (19-20) : 497 - 500
  • [8] Role of SPECT/CT in Sentinel Lymph Node Detection in Patients With Breast Cancer
    Vercellino, Laetitia
    Ohnona, Jessica
    Groheux, David
    Slama, Abdelhak
    Colletti, Patrick M.
    Chondrogiannis, Sotirios
    Merlet, Pascal
    Toubert, Marie-Elisabeth
    Rubello, Domenico
    CLINICAL NUCLEAR MEDICINE, 2014, 39 (05) : 431 - 436
  • [9] Radiopharmaceuticals for sentinel lymph node identification in breast cancer
    Shahsavari, Fahime
    Kashi, Mohsen Bakhshi
    Farzanefar, Saeed
    Eppard, Elisabeth
    Vahidfar, Nasim
    JOURNAL OF RADIOANALYTICAL AND NUCLEAR CHEMISTRY, 2023, 332 (07) : 2409 - 2417
  • [10] Preoperative identification of the sentinel lymph node in breast cancer
    Nathanson, S. David
    Burke, Matthew
    Slater, Robert
    Kapke, Alissa
    ANNALS OF SURGICAL ONCOLOGY, 2007, 14 (11) : 3102 - 3110