Shaping Silver Nanoparticles' Size through the Carrier Composition: Synthesis and Antimicrobial Activity

被引:4
作者
Cacaci, Margherita [1 ,2 ]
Biagiotti, Giacomo [3 ,4 ]
Toniolo, Gianluca [3 ,4 ]
Albino, Martin [3 ,5 ]
Sangregorio, Claudio [5 ]
Severi, Mirko [3 ]
Di Vito, Maura [1 ]
Squitieri, Damiano [1 ]
Contiero, Luca [6 ]
Paggi, Marco [7 ]
Marelli, Marcello [8 ]
Cicchi, Stefano [3 ,4 ]
Bugli, Francesca [1 ,2 ]
Richichi, Barbara [3 ,4 ]
机构
[1] Univ Cattolica Sacro Cuore, Dipartimento Sci Biotecnolog Base, Clin Intensivolog & Perioperatorie, I-00168 Rome, Italy
[2] Fdn Policlin Univ A Gemelli IRCCS, Dipartimento Sci Lab & Infettivolog, I-00168 Rome, Italy
[3] Univ Firenze, Dept Chem Ugo Schiff, Via Lastruccia 13, I-50019 Sesto Fiorentino, Italy
[4] Consorzio Interuniv Nazl Sci & Tecnol Materiali IN, I-50121 Florence, Italy
[5] ICCOM CNR, Via Madonna Piano 10, I-50019 Sesto Fiorentino, Italy
[6] Cromol Italia SpA, ZI Porcari, I-55016 Lucca, Italy
[7] IMT Sch Adv Studies Lucca, Piazza San Francesco 19, I-55100 Lucca, Italy
[8] CNR SCITEC Ist Sci & Tecnol Chim Giulio Natta, Via Fantoli 16-15, I-20138 Milan, Italy
关键词
silver nanoparticles; graphene oxide; salicylic acid; titanium dioxide; antimicrobial resistance; RESISTANCE;
D O I
10.3390/nano13101585
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The increasing resistance of bacteria to conventional antibiotics represents a severe global emergency for human health. The broad-spectrum antibacterial activity of silver has been known for a long time, and silver at the nanoscale shows enhanced antibacterial activity. This has prompted research into the development of silver-based nanomaterials for applications in clinical settings. In this work, the synthesis of three different silver nanoparticles (AgNPs) hybrids using both organic and inorganic supports with intrinsic antibacterial properties is described. The tuning of the AgNPs' shape and size according to the type of bioactive support was also investigated. Specifically, the commercially available sulfated cellulose nanocrystal (CNC), the salicylic acid functionalized reduced graphene oxide (rGO-SA), and the commercially available titanium dioxide (TiO2) were chosen as organic (CNC, rGO-SA) and inorganic (TiO2) supports. Then, the antimicrobial activity of the AgNP composites was assessed on clinically relevant multi-drug-resistant bacteria and the fungus Candida albicans. The results show how the formation of Ag nanoparticles on the selected supports provides the resulting composite materials with an effective antibacterial activity.
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页数:11
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共 31 条
[1]   Development of carboxymethyl cellulose-based hydrogel and nanosilver composite as antimicrobial agents for UTI pathogens [J].
Alshehri, Saad M. ;
Aldalbahi, Ali ;
Al-Hajji, Abdullah Baker ;
Chaudhary, Anis Ahmad ;
Panhuis, Marc In Het ;
Alhokbany, Norah ;
Ahamad, Tansir .
CARBOHYDRATE POLYMERS, 2016, 138 :229-236
[2]   Antibiotic resistance in hospital-acquired ESKAPE-E infections in low- and lower-middle-income countries: a systematic review and meta-analysis [J].
Ayobami, Olaniyi ;
Brinkwirth, Simon ;
Eckmanns, Tim ;
Markwart, Robby .
EMERGING MICROBES & INFECTIONS, 2022, 11 (01) :443-451
[3]   Novel Antibacterials: Alternatives to Traditional Antibiotics [J].
Betts, Jonathan W. ;
Hornsey, Michael ;
La Ragione, Roberto M. .
ADVANCES IN MICROBIAL PHYSIOLOGY, VOL 73, 2018, 73 :123-169
[4]   Simple engineering of hybrid cellulose nanocrystal-gold nanoparticles results in a functional glyconanomaterial with biomolecular recognition properties [J].
Biagiotti, Giacomo ;
Toniolo, Gianluca ;
Albino, Martin ;
Severi, Mirko ;
Andreozzi, Patrizia ;
Marelli, Marcello ;
Kokot, Hana ;
Tria, Giancarlo ;
Guerri, Annalisa ;
Sangregorio, Claudio ;
Rojo, Javier ;
Berti, Debora ;
Marradi, Marco ;
Cicchi, Stefano ;
Urbancic, Iztok ;
van Kooyk, Yvette ;
Chiodo, Fabrizio ;
Richichi, Barbara .
NANOSCALE HORIZONS, 2023, 8 (06) :776-782
[5]   Metal-Free Antibacterial Additives Based on Graphene Materials and Salicylic Acid: From the Bench to Fabric Applications [J].
Biagiotti, Giacomo ;
Salvatore, Annalisa ;
Toniolo, Gianluca ;
Caselli, Lucrezia ;
Di Vito, Maura ;
Cacaci, Margherita ;
Contiero, Luca ;
Gori, Tommaso ;
Maggini, Michele ;
Sanguinetti, Maurizio ;
Berti, Debora ;
Bugli, Francesca ;
Richichi, Barbara ;
Cicchi, Stefano .
ACS APPLIED MATERIALS & INTERFACES, 2021, 13 (22) :26288-26298
[6]   Silver Nanoparticles and Their Antibacterial Applications [J].
Bruna, Tamara ;
Maldonado-Bravo, Francisca ;
Jara, Paul ;
Caro, Nelson .
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (13)
[7]   Advances on catalytic reduction of 4-nitrophenol by nanostructured materials as benchmark reaction [J].
Das, Tushar Kanti ;
Das, Narayan Ch. .
INTERNATIONAL NANO LETTERS, 2022, 12 (03) :223-242
[8]   Mussel-inspired Ag/poly(norepinephrine)/MnO2 heterogeneous nanocatalyst for efficient reduction of 4-nitrophenol and 4-nitroaniline: an alternative approach [J].
Das, Tushar Kanti ;
Ganguly, Sayan ;
Remanan, Sanjay ;
Ghosh, Sabyasachi ;
Das, Narayan Ch. .
RESEARCH ON CHEMICAL INTERMEDIATES, 2020, 46 (07) :3629-3650
[9]   Benchmarking Cellulose Nanocrystals Part II: New Industrially Produced Materials [J].
Delepierre, Gwendoline ;
Vanderfleet, Oriana M. ;
Niinivaara, Elina ;
Zakani, Behzad ;
Cranston, Emily D. .
LANGMUIR, 2021, 37 (28) :8393-8409
[10]   An Updated Review on Silver Nanoparticles in Biomedicine [J].
Gherasim, Oana ;
Puiu, Rebecca Alexandra ;
Birca, Alexandra Catalina ;
Burdusel, Alexandra-Cristina ;
Grumezescu, Alexandru Mihai .
NANOMATERIALS, 2020, 10 (11) :1-44