DIABETES MELLITUS AGGRAVATES BEHAVIORAL DEFICIT AND INCREASES SITE-SPECIFIC PHOSPHORYLATION OF TAU PROTEIN IN ALZHEIMER'S DISEASE MOUSE MODEL.

被引:0
|
作者
Ito, Yuki [1 ,2 ]
Takeda, Shuko [1 ,2 ]
Nakajima, Tsuneo [3 ]
Oyama, Akane [2 ,3 ]
Takeshita, Hikari [3 ]
Miki, Kunihiro [1 ]
Takami, Yoichi [3 ]
Takeya, Yasushi [3 ,4 ]
Shimamura, Munehisa [5 ]
Rakugi, Hiromi [3 ]
Morishita, Ryuichi [1 ]
机构
[1] Osaka Univ, Grad Sch Med, Dept Clin Gene Therapy, Suita, Osaka, Japan
[2] Osaka Psychiat Med Ctr, Osaka Psychiat Res Ctr, Osaka, Japan
[3] Osaka Univ, Grad Sch Med, Dept Geriatr & Gen Med, Suita, Osaka, Japan
[4] Osaka Univ, Grad Sch Med, Div Hlth Sci, Dept Clin Nursing, Suita, Osaka, Japan
[5] Osaka Univ, Dept Hlth Dev & Med, Dept Neurol, Suita, Osaka, Japan
关键词
D O I
暂无
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
PS-B05-10
引用
收藏
页码:E365 / E365
页数:1
相关论文
共 50 条
  • [31] High-Fat Diet-Induced Diabetic Conditions Exacerbate Cognitive Impairment in a Mouse Model of Alzheimer’s Disease Via a Specific Tau Phosphorylation Pattern
    Y. Ito
    Shuko Takeda
    T. Nakajima
    A. Oyama
    H. Takeshita
    K. Miki
    Y. Takami
    Y. Takeya
    M. Shimamura
    H. Rakugi
    Ryuichi Morishita
    The Journal of Prevention of Alzheimer's Disease, 2024, 11 : 138 - 148
  • [32] Selenomethionine Ameliorates Cognitive Decline, Reduces Tau Hyperphosphorylation, and Reverses Synaptic Deficit in the Triple Transgenic Mouse Model of Alzheimer's Disease
    Song, Guoli
    Zhang, Zhonghao
    Wen, Lei
    Chen, Chen
    Shi, Qingxue
    Zhang, Yu
    Ni, Jiazuan
    Liu, Qiong
    JOURNAL OF ALZHEIMERS DISEASE, 2014, 41 (01) : 85 - 99
  • [33] Evaluating Effects of Glatiramer Acetate Treatment on Amyloid Deposition and Tau Phosphorylation in the 3xTg Mouse Model of Alzheimer's Disease
    Dionisio-Santos, Dawling A.
    Karaahmet, Berke
    Belcher, Elizabeth K.
    Owlett, Laura D.
    Trojanczyk, Lee A.
    Olschowka, John A.
    O'Banion, M. Kerry
    FRONTIERS IN NEUROSCIENCE, 2021, 15
  • [34] CB2 Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer's Disease
    Koppel, Jeremy
    Vingtdeux, Valerie
    Marambaud, Philippe
    d'Abramo, Cristina
    Jimenez, Heidy
    Stauber, Mark
    Friedman, Rachel
    Davies, Peter
    MOLECULAR MEDICINE, 2013, 19 : 357 - 364
  • [35] CB2 Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer’s Disease
    Jeremy Koppel
    Valerie Vingtdeux
    Philippe Marambaud
    Cristina d’Abramo
    Heidy Jimenez
    Mark Stauber
    Rachel Friedman
    Peter Davies
    Molecular Medicine, 2013, 19 : 29 - 36
  • [36] CB2 Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer's Disease
    Koppel, Jeremy
    Vingtdeux, Valerie
    Marambaud, Philippe
    d'Abramo, Cristina
    Jimenez, Heidy
    Stauber, Mark
    Friedman, Rachel
    Davies, Peter
    MOLECULAR MEDICINE, 2014, 20 : 29 - 36
  • [37] CB2 Receptor Deficiency Increases Amyloid Pathology and Alters Tau Processing in a Transgenic Mouse Model of Alzheimer’s Disease
    Jeremy Koppel
    Valerie Vingtdeux
    Philippe Marambaud
    Cristina d’Abramo
    Heidy Jimenez
    Mark Stauber
    Rachel Friedman
    Peter Davies
    Molecular Medicine, 2014, 20 : 29 - 36
  • [38] Stabilizing the Retromer Complex in a Human Stem Cell Model of Alzheimer's Disease Reduces TAU Phosphorylation Independently of Amyloid Precursor Protein
    Young, Jessica E.
    Fong, Lauren K.
    Frankowski, Harald
    Petsko, Gregory A.
    Small, Scott A.
    Goldstein, Lawrence S. B.
    STEM CELL REPORTS, 2018, 10 (03): : 1046 - 1058
  • [39] Neoline Improves Memory Impairment and Reduces Amyloid-β Level and Tau Phosphorylation Through AMPK Activation in the Mouse Alzheimer's Disease Model
    Liu, Quan Feng
    Kanmani, Suganya
    Lee, Jinhyuk
    Kim, Geun-Woo
    Jeon, Songhee
    Koo, Byung-Soo
    JOURNAL OF ALZHEIMERS DISEASE, 2021, 81 (02) : 507 - 516
  • [40] Intravenous administration of mesenchymal stem cells reduces Tau phosphorylation and inflammation in the 3xTg-AD mouse model of Alzheimer's disease
    Neves, Amanda Ferreira
    Camargo, Christian
    Premer, Courtney
    Hare, Joshua M.
    Baumel, Bernard S.
    Pinto, Milena
    EXPERIMENTAL NEUROLOGY, 2021, 341