Effects of early human immunodeficiency virus infection on cerebral white matter blood flow autoregulation

被引：0

作者：

Sen, Souvik ^{[1
]}

An, Hongyu ^{[2
]}

Oakes, Jonathan ^{[3
]}

Eron, Joseph ^{[3
]}

Robertson, Kevin ^{[3
]}

Powers, William ^{[3
,4
]}

机构：

[1] Univ South Carolina, Columbia, SC 29208 USA

[2] Washington Univ, St Louis, MO 63110 USA

[3] Univ N Carolina, Chapel Hill, NC 27515 USA

[4] Duke Univ, Durham, NC USA

来源：

AIDS | 2023年 / 37卷 / 02期

关键词：

HIV; HYPOTENSION;

D O I：

10.1097/QAD.0000000000003378

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Blood flow autoregulation in cerebral white matter was measured before and after acute nicardipine-induced changes in mean arterial pressure of 10-21% in 21 treatment naive HIV-positive adults and 32 controls. The autoregulatory index (-% cerebral blood flow change/% mean arterial pressure change) was not different at baseline (P = 0.71) or after 1 year of treatment (n = 11, P = 0.17). We found no autoregulatory defect to explain the increased stroke risk or the development of cerebral white damage in people with HIV.

引用

页码：359 / 361

页数：3

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