Nerve biopsy in T-cell lymphoma with neurolymphomatosis: where and when

被引:0
作者
Pipis, Menelaos [1 ,2 ]
Jaunmuktane, Zane [3 ,4 ]
Marafioti, Teresa [5 ]
Brandner, Sebastian [3 ,6 ]
Smith, Elaine C. [7 ]
D'Sa, Shirley [8 ]
Lunn, Michael P. [1 ]
Cwynarski, Kate [8 ]
Fialho, Doreen [9 ]
Shah, Sachit [10 ]
Fuller, Geraint N. [11 ]
Reilly, Mary M. [1 ]
机构
[1] UCL Queen Sq Inst Neurol, Ctr Neuromuscular Dis, London, England
[2] Guys & St Thomas NHS Fdn Trust, Dept Hematol, London, England
[3] Natl Hosp Neurol & Neurosurg, UCLH NHS Fdn Trust, Dept Neuropathol, London, England
[4] UCL Queen Sq Inst Neurol, Dept Clin & Movement Neurosci, London, England
[5] Univ Coll London Hosp NHS Fdn Trust, Dept Histopathol, London, England
[6] UCL Queen Sq Inst Neurol, Dept Neurodegenerat Dis, London, England
[7] Cheltenham Gen Hosp, Dept Rheumatol, Cheltenham, England
[8] UCLH NHS Fdn Trust, Dept Clin Haematol, London, England
[9] Guys & St Thomas NHS Fdn Trust, Dept Clin Neurophysiol, London, England
[10] Natl Hosp Neurol & Neurosurg, UCLH NHS Fdn Trust, Dept Neuroradiol, London, England
[11] Gloucestershire Hosp NHS Fdn Trust, Dept Neurol, Gloucester, England
关键词
CLINICAL NEUROLOGY; HAEMATOLOGY; PERIPHERAL NEUROPATHOLOGY; CHRONIC LIVER-DISEASE; HEPATIC-ENCEPHALOPATHY; BACTERIAL-MENINGITIS; IMMUNE DYSFUNCTION; MYELINOLYSIS; PREVALENCE; DIAGNOSIS; CARE;
D O I
10.1136/pn-2023-003992
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Peripheral T-cell lymphomas are rare heterogeneous haematological malignancies that may also involve peripheral nerves in a very small subset of cases. We report a patient with a diagnostically challenging cutaneous T-cell lymphoma and multifocal mononeuropathies in whom a targeted nerve biopsy identified lymphomatous infiltration of nerves and expedited combination treatment with chemotherapy and an autologous stem cell transplant. She showed an excellent response with a complete metabolic response on positron emission tomography imaging and significant clinical improvement, maintained 5 years post-treatment.
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收藏
页码:235 / 237
页数:4
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