Enhancing Biocompatibility and Antibacterial Activity of Ti6Al4V by Entrapping Ag and Hydroxyapatite Inside Alginate Filled Pores of TiO2 Layer Grown by Spark Anodizing

被引：3
|
作者：
Pupillo, Davide [1 ]
Zaffora, Andrea [2 ]
Di Franco, Francesco [2 ]
Picone, Pasquale [3 ,4 ]
Nuzzo, Domenico [3 ,4 ]
Santamaria, Monica [2 ]
机构：
[1] Politecn Torino, Dipartimento Sci Applicata & Tecnol, Corso Duca Abruzzi 24, I-10129 Turin, Italy
[2] Univ Palermo, Dipartimento Ingn, Viale Sci, Ed 6, I-90128 Palermo, Italy
[3] CNR, Ist Ric & Innovaz Biomed, I-90146 Palermo, Italy
[4] Univ Palermo, Dipartimento Sci & Tecnol Biol Chim & Farmaceut, Viale Sci, Ed 16, I-90128 Palermo, Italy
来源：
ADVANCED MATERIALS INTERFACES | 2023年 / 10卷 / 02期
关键词：
Ag; alginate; antibacterial activity; bioactivity; hydroxyapatite; Ti alloys; TITANIUM; COATINGS; SILVER; ALLOY; TI-6AL-4V; FILMS;
D O I：
10.1002/admi.202201725
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A three-step electrochemical process is developed to grow a coating on Ti6Al4V alloy for biomedical applications aimed to enhance its bioactivity. The coating is composed by a porous titanium oxide filled with Ag, alginic acid, and hydroxyapatite to provide antibacterial properties and, at the same time, osteointegration capability. Anodized and treated with the electrochemical process samples are characterized by Scanning Electron Microscopy (SEM), Energy-Dispersive X-ray Spectroscopy (EDX), X-Ray Diffraction, and Raman Spectroscopy to have information about morphology and composition soon after the fabrication and after immersion in Hanks' solution. Bioactivity of the samples is also proved by electrochemical tests through Electrochemical Impedance Spectroscopy (EIS) measurements. Antibacterial properties, cytocompatibility and hemocompatibility of the samples are successfully demonstrated by in vitro tests.
引用
收藏
页数：12
相关论文
共 50 条
  • [41] Comparison of Mechanical and Antibacterial Properties of TiO2/Ag Ceramics and Ti6Al4V-TiO2/Ag Composite Materials Using Combined SLM-SPS Techniques
    Rahmani, Ramin
    Rosenberg, Merilin
    Ivask, Angela
    Kollo, Lauri
    METALS, 2019, 9 (08)
  • [42] Ta2O5-doped TiO2 nanotubes on Ti6Al4V alloy with improved cytocompatibility to endothelial cells
    Zhang, Meng
    Wang, Yongsheng
    Jia, Wenru
    Ma, Dandan
    Huang, Xiaobo
    Yu, Shengwang
    Wu, Yucheng
    VACUUM, 2022, 195
  • [43] Evaluating the cell migration potential of TiO2 nanorods incorporated in a Ti6Al4V scaffold: A multiscale approach
    Gupta, Abhisek
    Das, Ankita
    Barui, Ananya
    Das, Apurba
    Chowdhury, Amit Roy
    JOURNAL OF THE MECHANICAL BEHAVIOR OF BIOMEDICAL MATERIALS, 2023, 144
  • [44] Antimicrobial property, cytocompatibility and corrosion resistance of Zn-doped ZrO2/TiO2 coatings on Ti6Al4V implants
    Wang, Ruoyun
    He, Xiaojing
    Gao, Yuee
    Zhang, Xiangyu
    Yao, Xiaohong
    Tang, Bin
    MATERIALS SCIENCE AND ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 2017, 75 : 7 - 15
  • [45] On Growth and Morphology of TiO2 Nanotubes on Ti6Al4V by Anodic Oxidation in Ethylene Glycol Electrolyte: Influence of Microstructure and Anodization Parameters
    Ribeiro, Bruno
    Offoiach, Ruben
    Rahimi, Ehsan
    Salatin, Elisa
    Lekka, Maria
    Fedrizzi, Lorenzo
    MATERIALS, 2021, 14 (10)
  • [46] Sol-gel preparation, corrosion resistance and hydrophilicity of Ta-containing TiO2 films on Ti6Al4V alloy
    Fu, Tao
    Sun, Jian-min
    Alajmi, Zafer
    Wu, Feng
    TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA, 2015, 25 (02) : 471 - 476
  • [47] Evaluation of different topography of TiO2 nanotube morphologies on Ti6Al4V alloy plate for in-vitro studies in orthopaedic application
    Poddar, Shashank
    Bit, Arindam
    Sinha, Sudip K.
    BULLETIN OF MATERIALS SCIENCE, 2023, 46 (03)
  • [48] Preparation and tribological properties of self-lubricating TiO2/graphite composite coating on Ti6Al4V alloy
    Mu, Ming
    Zhou, Xinjian
    Xiao, Qian
    Liang, Jun
    Huo, Xiaodi
    APPLIED SURFACE SCIENCE, 2012, 258 (22) : 8570 - 8576
  • [49] Structure and visible photocatalytic activity of nitrogen-doped meso-porous TiO2 layer on Ti6Al4V substrate by plasma-based ion implantation
    Li Jin-long
    Ma Xin-xin
    Sun Ming-ren
    Li Xiao-min
    Song Zhen-lun
    TRANSACTIONS OF NONFERROUS METALS SOCIETY OF CHINA, 2009, 19 : S665 - S668
  • [50] High temperature oxidation behavior of TiO2 + ZrO2 composite ceramic coatings prepared by microarc oxidation on Ti6Al4V alloy
    Wang, Chao
    Hao, Jianmin
    Xing, Yazhe
    Guo, Chaofei
    Chen, Hong
    SURFACE & COATINGS TECHNOLOGY, 2015, 261 : 201 - 207
12345