Black-White Risk Differentials in Pediatric COVID-19 Hospitalization and Intensive Care Unit Admissions in the USA

被引:11
作者
Holmes, Laurens, Jr. [1 ,7 ,8 ]
Wu, Colin [2 ]
Hinson, Rakinya [1 ,3 ]
Dias, Emanuelle [1 ,4 ]
Nelson, Carlin [1 ,5 ]
Pelaez, Lavisha [1 ]
Dabney, Kirk [1 ,6 ]
Whaley, Kayla [1 ,6 ]
Williams, Justin [1 ]
机构
[1] Nemours Childrens Healthcare Syst, Off Hlth Equ & Inclus OHEI, Wilmington, DE 19802 USA
[2] Tufts Univ, Biol Dept, Medford, MA 02155 USA
[3] Florida A&M Univ, Inst Publ Hlth, Dept Epidemiol & Biostat, Tallahassee, FL 32307 USA
[4] Univ Texas Hlth Sci Ctr Houston, Sch Publ Hlth, Dept Hlth Promot & Behav Sci, Houston, TX 77030 USA
[5] Walden Univ, Coll Hlth Profess, Minneapolis, MN USA
[6] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA 30322 USA
[7] Univ Delaware, Biol Sci Dept, Newark, DE 19716 USA
[8] Global Epigen Res & Analyt, Wilmington, DE 19802 USA
关键词
COVID-19; Hospitalization; ICU; Children; Race/ethnicity; ANDROGEN DEPRIVATION THERAPY; RACIAL/ETHNIC DISPARITIES; SURVIVAL;
D O I
10.1007/s40615-022-01305-7
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Purpose The COVID-19 morbidity with SARS-CoV-2 as a causative pathogenic microbe remains a pandemic with children experiencing less mortality but with severe manifestations. The current study aimed to assess SARS-CoV-2 cumulative incidence, COVID-19 hospitalization, and ICU admission with respect to racial differentials. Materials and Methods A cross-sectional nonexperimental epidemiologic design was used to examine pediatric COVID-19 data from CDC during 2020. The variables assessed were ICU admissions, hospitalization, sex, race, and region. The Chi-Square (X-2) statistic was used to examine the independence of the variables by race, while the binomial regression model was used to predict racial risk differentials in hospitalization and ICU admissions. Results The pediatric COVID-19 data observed the cumulative incidence of hospitalization to be 96,376, while ICU admission was 12,448. Racial differences were observed in hospitalization, ICU admissions, sex, and region. With respect to COVID-19 hospitalization, Black/African American (AA) children were two times as likely to be hospitalized compared to their White counterparts, prevalence risk ratio (pRR)= 2.20, 99% confidence interval (CI= 2.12-2.28). Similarly, Asians were 45% more likely to be hospitalized relative to their White counterparts, pRR= 1.45, 99% CI= 1.32-1.60. Regarding ICU admission, there was a disproportionate racial burden, implying excess ICU admission among Black/AA children relative to their White counterparts, pRR= 5.18, 99% CI= 4.44-6.04. Likewise, Asian children were 3 times as likely to be admitted to the ICU compared to their White counterparts, pRR= 3.36, 99% CI= 2.37-4.77. Additionally, American Indians/Alaska Natives were 2 times as likely to be admitted to ICU, pRR= 2.54, 99% CI= 0.82-7.85. Conclusion Racial disparities were observed in COVID-19 hospitalization and ICU admission among the US children, with Black/AA children being disproportionately affected, implying health equity transformation.
引用
收藏
页码:1187 / 1193
页数:7
相关论文
共 23 条
[1]  
Alfishawy M, 2020, INT J TRANSPLANT MED, V11, P145
[2]   Visualizing COVID-19 Mortality Rates and African-American Populations in the USA and Pennsylvania [J].
Anaele, Beverly I. ;
Doran, Cierrah ;
McIntire, Russell .
JOURNAL OF RACIAL AND ETHNIC HEALTH DISPARITIES, 2021, 8 (06) :1356-1363
[3]   Intensive care unit patients with 2009 pandemic influenza A (H1N1pdm09) virus infection - United States, 2009 [J].
Bramley, Anna M. ;
Dasgupta, Sharoda ;
Skarbinski, Jacek ;
Kamimoto, Laurie ;
Fry, Alicia M. ;
Finelli, Lyn ;
Jain, Seema .
INFLUENZA AND OTHER RESPIRATORY VIRUSES, 2012, 6 (06) :e134-e142
[4]   The Impact of Pre-existing Comorbidities and Therapeutic Interventions on COVID-19 [J].
Callender, Lauren A. ;
Curran, Michelle ;
Bates, Stephanie M. ;
Mairesse, Maelle ;
Weigandt, Julia ;
Betts, Catherine J. .
FRONTIERS IN IMMUNOLOGY, 2020, 11
[5]  
CDC COVID-19 Response Team, 2020, MMWR-MORBID MORTAL W, V69, P343, DOI [10.15585/mmwr.mm6912e2, 10.15585/mmwr.mm6915e4]
[6]   Racial Disparities in COVID-19 Testing and Outcomes Retrospective Cohort Study in an Integrated Health System [J].
Escobar, Gabriel J. ;
Adams, Alyce S. ;
Liu, Vincent X. ;
Soltesz, Lauren ;
Chen, Yi-Fen Irene ;
Parodi, Stephen M. ;
Ray, G. Thomas ;
Myers, Laura C. ;
Ramaprasad, Charulata M. ;
Dlott, Richard ;
Lee, Catherine .
ANNALS OF INTERNAL MEDICINE, 2021, 174 (06) :786-+
[7]   Effectiveness of androgen deprivation therapy in prolonging survival of older men treated for locoregional prostate cancer [J].
Holmes, L., Jr. ;
Chan, W. ;
Jiang, Z. ;
Du, X. L. .
PROSTATE CANCER AND PROSTATIC DISEASES, 2007, 10 (04) :388-395
[8]   Black-White Risk Differentials in COVID-19 (SARS-COV2) Transmission, Mortality and Case Fatality in the United States: Translational Epidemiologic Perspective and Challenges [J].
Holmes, Laurens, Jr. ;
Enwere, Michael ;
Williams, Janille ;
Ogundele, Benjamin ;
Chavan, Prachi ;
Piccoli, Tatiana ;
Chinaka, Chinacherem ;
Comeaux, Camillia ;
Pelaez, Lavisha ;
Okundaye, Osatohamwen ;
Stalnaker, Leslie ;
Kalle, Fanta ;
Deepika, Keeti ;
Philipcien, Glen ;
Poleon, Maura ;
Ogungbade, Gbadebo ;
Elmi, Hikma ;
John, Valescia ;
Dabney, Kirk W. .
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 2020, 17 (12) :1-18
[9]   Impact of Androgen Deprivation Therapy on Racial/Ethnic Disparities in the Survival of Older Men Treated for Locoregional Prostate Cancer [J].
Holmes, Laurens, Jr. ;
Chan, Wenyaw ;
Jiang, Zhidong ;
Ward, Doriel ;
Essien, E. James ;
Du, Xianglin L. .
CANCER CONTROL, 2009, 16 (02) :176-185
[10]  
Lange Klaus W, 2020, Glob Health J, V4, P146, DOI [10.1016/j.glohj.2020.11.002, 10.1016/j.glohj.2020.11.002]