Direct electrochemical C-3 arylation of Quinoxalin-2(1H)- ones with cyanoaromatics via paired electrolysis

被引：1

作者：

Deng, Yang ^{[1
]}

Wang, Xiao-Wen ^{[1
]}

Lv, Jin-Feng ^{[1
]}

Guan, Zhi ^{[1
]}

He, Yan-Hong ^{[1
]}

机构：

[1] Southwest Univ, Sch Chem & Chem Engn, Key Lab Appl Chem Chongqing Municipal, Chongqing 400715, Peoples R China

来源：

TETRAHEDRON | 2024年 / 153卷

基金：

中国国家自然科学基金;

关键词：

Arylation; Quinoxalin-2(1H)-Ones; Cyanoaromatics; Electrochemistry; Paired electrolysis; IN-VITRO; DESIGN; DERIVATIVES; INHIBITORS; POTENT; METAL; STRATEGIES; ACIDS;

D O I：

10.1016/j.tet.2024.133839

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and environmentally friendly electrochemical process is described for the direct C-3 arylation of quinoxalin-2(1H)-ones using readily available cyanoaromatics through paired electrolysis. The reaction features excellent atom economy, mild reaction conditions and simple operation (using undivided electrolytic cells at ambient temperature), without the need for oxidants, catalysts, metals, or sacrificial reagents. It offers a practical method of synthesizing 3-arylquinoxalin-2(1H)-one derivatives.

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页数：5

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