Use of a novel smartphone-based application tool for enrolment and randomisation in pre-hospital clinical trials

被引：4

作者：

Bloom, Jason E. ^{[3
,4
,5
,6
]}

Partovi, Andi ^{[7
]}

Bernard, Stephen ^{[5
]}

Okyere, Daniel ^{[6
]}

Heritier, Stephane ^{[5
]}

Mahony, Emily ^{[6
]}

Eliakundu, Amminadab L. ^{[5
]}

Dawson, Luke P. ^{[3
,5
]}

Voskoboinik, Aleksandr ^{[3
,4
]}

Anderson, David ^{[6
,8
]}

Ball, Jocasta ^{[5
]}

Chan, William ^{[3
,4
]}

Kaye, David M. ^{[3
,4
]}

Nehme, Ziad ^{[6
,8
]}

Stub, Dion ^{[1
,2
,3
,4
,6
]}

机构：

[1] Alfred Hosp, 55 Commercial Rd, Prahran, Vic 3004, Australia

[2] Monash Univ, 55 Commercial Rd, Prahran, Vic 3004, Australia

[3] Alfred Hlth, Dept Cardiol, 55 Commercial Rd, Melbourne, Vic 3004, Australia

[4] Baker Heart & Diabet Inst, 75 Commercial Rd, Melbourne, Vic 3004, Australia

[5] Monash Univ, Sch Publ Hlth & Prevent Med, 553 St Kilda Rd, Melbourne, Vic 3004, Australia

[6] Ambulance Victoria, 31 Joseph St, Blackburn, Vic 3130, Australia

[7] KeyLead Hlth, Melbourne, Vic, Australia

[8] Monash Univ, Dept Paramedicine, McMahons Rd, Frankston, Vic 3199, Australia

来源：

RESUSCITATION | 2023年 / 187卷

基金：

英国医学研究理事会; 澳大利亚国家健康与医学研究理事会;

关键词：

Randomised controlled trial; Methods; Smartphone; Trial design; HOSPITAL CARDIAC-ARREST; THERAPEUTIC HYPOTHERMIA; CARDIOPULMONARY-RESUSCITATION; VENTRICULAR-FIBRILLATION; CHEST COMPRESSIONS; INDUCTION; SURVIVAL; DEFIBRILLATION; INFUSION; ACCESS;

D O I：

10.1016/j.resuscitation.2023.109787

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

The effective recruitment and randomisation of patients in pre-hospital clinical trials presents unique challenges. Owing to the time critical nature of many pre-hospital emergencies and limited resourcing, the use of traditional methods of randomisation that may include centralised telephone or web-based systems are often not practicable or feasible. Previous technological limitations have necessitated that pre-hospital trialists strike a com-promise between implementing pragmatic, deliverable study designs, with robust enrolment and randomisation methodologies. In this commentary piece, we present a novel smartphone-based solution that has the potential to align pre-hospital clinical trial recruitment processes to that of best-in -practice in-hospital and ambulatory care based studies.

引用

页数：6

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