Bond strength of CAD/CAM denture teeth to a denture base resin in a milled monolithic unit

Purpose: Herein, the bond strength (BS) of denture teeth to a denture base resin in a milled monolithic unit was investi-gated and compared with those of 3D printed teeth to a 3D printed denture base and prefabricated teeth to a heat-cured acrylic resin before and after thermocycling.Methods: Sixty specimens of a denture tooth attached to a cylindrical denture base were fabricated following ISO Stan-dard 19736. Three fabrication techniques-3D printing, conventional compression molding, and milling using monolithic technology-were employed to mill teeth and denture base parts as a single unit. The BS was investigated before and after thermocycling. Data were statistically analyzed using the Kruskal-Wallis test with Bonferroni correction (alpha = 0.05).Results: Before thermocycling, the mean BS of the milled group was significantly higher than that of the conventional group (P = 0.002). The 3D printed group showed no statistically significant difference from the milled (P = 0.051) and conventional (P = 0.824) groups. After thermocycling, although the mean BS values of the milled (P = 0.00) and 3D printed (P = 0.01) groups were significantly higher than that of the conventional group, there was no significant difference between them (P = 0.226). Only the BS of the conventional group was significantly reduced by thermocycling (P = 0.00).Conclusions: The milled monolithic fabrication technique, which eliminates the need for a bonding step, offered a promising combination of high-precision digital fabrication and a significantly high BS. The BS of the conventional group significantly decreased after thermocycling.