Ambient PM2.5 and cardiopulmonary mortality in the oldest-old people in China: A national time-stratified case-crossover study

被引:4
作者
Wu, Cuiling [1 ,2 ]
He, Guanhao [1 ,2 ]
Wu, Wei [3 ]
Meng, Ruilin [4 ]
Zhou, Chunliang [5 ]
Bai, Guoxia [6 ]
Yu, Min [7 ]
Gong, Weiwei
Huang, Biao [8 ]
Xiao, Yize [9 ]
Hu, Jianxiong [3 ]
Xiao, Jianpeng [3 ]
Zeng, Fangfang [1 ,2 ]
Yang, Pan [1 ,2 ]
Liu, Dan [1 ,2 ]
Zhu, Qijiong [1 ,2 ]
Chen, Zhiqing [1 ,2 ]
Yu, Siwen [1 ,2 ]
Huang, Cunrui [10 ]
Du, Yaodong [11 ]
Liang, Xiaofeng [1 ,2 ]
Liu, Tao [1 ,2 ]
Ma, Wenjun [1 ,2 ]
机构
[1] Jinan Univ, Sch Med, Dept Publ Hlth & Prevent Med, Guangzhou 510632, Peoples R China
[2] Jinan Univ, China Greater Bay Area Res Ctr Environm Hlth, Sch Med, Guangzhou 510632, Peoples R China
[3] Jinan Univ, Dis Control & Prevent Inst, Guangzhou 510632, Peoples R China
[4] Guangdong Prov Ctr Dis Control & Prevent, Guangdong Prov Inst Publ Hlth, Guangzhou 511430, Peoples R China
[5] Guangdong Prov Ctr Dis Control & Prevent, Guangzhou 511430, Peoples R China
[6] Hunan Prov Ctr Dis Control & Prevent, Dept Environm & Hlth, Changsha 450001, Peoples R China
[7] Tibet Ctr Dis Control & Prevent, Inst Noncommunicable Dis Prevent & Control, Lhasa 850000, Peoples R China
[8] Zhejiang Ctr Dis Control & Prevent, Hangzhou 310051, Zhejiang, Peoples R China
[9] Jilin Prov Ctr Dis Control & Prevent, Hlth Hazard Factors Control Dept, Changchun 130062, Peoples R China
[10] Yunnan Ctr Dis Control & Prevent, Kunming 650022, Peoples R China
[11] Tsinghua Univ, Vanke Sch Publ Hlth, Beijing 100084, Peoples R China
来源
MED | 2024年 / 5卷 / 01期
关键词
SHORT-TERM EXPOSURE; PARTICULATE AIR-POLLUTION; GLOBAL BURDEN; HEALTH; ASSOCIATION; POLLUTANTS; DISEASES; DEATHS; PM10; RISK;
D O I
10.1016/j.medj.2023.12.005
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Background: Evidence on the associations of fine particulate matter (PM2.5) with cardiopulmonary mortality in the oldest -old (aged 80+ years) people remains limited. Methods: We conducted a time -stratified case -crossover study of 1,475,459 deaths from cardiopulmonary diseases in China to estimate the associations between short-term exposure to ambient PM2.5 and cardiopulmonary mortality among the oldest -old people. Findings: Each 10 mg/m3 increase in PM2.5 concentration (6 -day moving average [lag05]) was associated with higher mortality from cardiopulmonary diseases (excess risks [ERs] = 1.69%, 95% confidence interval [CI]: 1.54%, 1.84%), cardiovascular diseases (ER = 1.72%, 95% CI: 1.54%, 1.90%), and respiratory diseases (ER = 1.62%, 95% CI: 1.33%, 1.91%). Compared to the other groups, females (ER = 1.94%, 95% CI: 1.73%, 2.15%) (p for difference test = 0.043) and those aged 95-99 years (ER = 2.31%, 95% CI: 1.61%, 3.02%) (aged 80-85 years old was the reference, p for difference test = 0.770) presented greater mortality risks. We found 14 specific cardiopulmonary causes associated with PM2.5, out of which emphysema (ER = 3.20%, 95% CI: 1.57%, 4.86%) had the largest association. Out of the total deaths, 6.27% (attributable fraction [AF], 95% CI: 5.72%, 6.82%) were ascribed to short-term PM2.5 exposure. Conclusions: This study provides evidence of PM2.5-induced cardiopulmonary mortality and calls for targeted prevention actions for the oldest -old people. Funding: This work was supported by the National Key Research and Development Program of China, the National Natural Science Foundation of China, the Foreign Expert Program of the Ministry of Science and Technology, the Natural Science Foundation of Guangdong, China, and the Science and Technology Program of Guangzhou.
引用
收藏
页码:62 / 72
页数:11
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