Administration of blue light in the morning and no blue-ray light in the evening improves the circadian functions of non-24-hour shift workers

被引：0

作者：

Zhong, Zhaomin ^{[1
,2
]}

Tan, Xiaohui ^{[1
,2
]}

An, Xingna ^{[1
,2
]}

Li, Jie ^{[1
,2
]}

Cai, Jing ^{[1
,2
]}

Jiang, Yunchun ^{[1
,2
]}

Taufique, S. K. Tahajjul ^{[1
,2
]}

Li, Bo ^{[1
,2
]}

Shi, Quan ^{[1
,2
]}

Zhao, Meng ^{[1
,2
]}

Wang, Yali ^{[3
]}

Luo, Qun ^{[4
]}

Wang, Han ^{[1
,2
]}

机构：

[1] Soochow Univ, Ctr Circadian Clocks, Suzhou, Jiangsu, Peoples R China

[2] Soochow Univ, Suzhou Med Coll, Sch Biol & Basic Med Sci, Suzhou, Jiangsu, Peoples R China

[3] Nanjing Med Univ, Dept Neurol, Affiliated Suzhou Hosp, Suzhou, Peoples R China

[4] PLA Naval Med Univ, Naval Med Ctr, Shanghai, Peoples R China

来源：

CHRONOBIOLOGY INTERNATIONAL | 2024年 / 41卷 / 02期

基金：

国家重点研发计划; 中国国家自然科学基金;

关键词：

Blue light; circadian clock; melatonin; non-24-hour shift; sleep; light spectrum-based intervention; WATCH SCHEDULES; SLEEP; NIGHT; MELATONIN; RHYTHMS; PERFORMANCE; METABOLISM; EXPOSURE; SYSTEM; SEA;

D O I：

10.1080/07420528.2024.2305218

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In modern 24-hour society, various round-the-clock services have entailed shift work, resulting in non-24-hour schedules. However, the extent of behavioral and physiological alterations by non-24-hour schedules remains unclear, and particularly, effective interventions to restore the circadian functions of non-24-hour shift workers are rarely explored. In this study, we investigate the effects of a simulated non-24-hour military shift work schedule on daily rhythms and sleep, and establish an intervention measure to restore the circadian functions of non-24-hour shift workers. The three stages of experiments were conducted. The stage-one experiment was to establish a comprehensive evaluation index of the circadian rhythms and sleep for all 60 participants by analyzing wristwatch-recorded physiological parameters and sleep. The stage-two experiment evaluated the effects of an intervention strategy on physiological rhythms and sleep. The stage-three experiment was to examine the participants' physiological and behavioral disturbances under the simulated non-24-hour military shift work schedule and their improvements by the optimal lighting apparatus. We found that wristwatch-recorded physiological parameters display robust rhythmicity, and the phases of systolic blood pressures and heart rates can be used as reliable estimators for the human body time. The simulated non-24-hour military shift work schedule significantly disrupts the daily rhythms of oxygen saturation levels, blood pressures, heart rates, and reduces sleep quality. Administration of blue light in the morning and no blue-ray light in the evening improves the amplitude and synchronization of daily rhythms of the non-24-hour participants. These findings demonstrate the harmful consequences of the non-24-hour shift work schedule and provide a non-invasive strategy to improve the well-being and work efficiency of the non-24-hour shift population.

引用

页码：267 / 282

页数：16

共 58 条

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