Ten-year follow-up of corneal cross-linking and refractive surface ablation in patients with asymmetric corneal topography

被引:1
作者
Moscovici, Bernardo Kaplan [1 ]
Rodrigues, Pablo Felipe [1 ]
Suehiro Dantas, Marcos Paulo [1 ]
Okimoto, Juliana Taemy [1 ]
Naves, Obidulho Sakassegawa [1 ]
de Carvalho Taguchi, Felipe Marques [1 ]
Nigro Santiago Malta, Joao Baptista [1 ]
Campos, Mauro [1 ]
机构
[1] Fed Univ Sao Paulo EPM UNIFESP, Paulista Sch Med, Dept Ophthalmol & Visual Sci, Sao Paulo, Brazil
关键词
Cornea; corneal stroma; corneal topography; excimer; lasers; photorefractive keratectomy; refractive surgery; TRANSEPITHELIAL PHOTOREFRACTIVE KERATECTOMY; GUIDED PRK; PROGRESSIVE KERATOCONUS; HAZE FORMATION; MITOMYCIN-C; ECTASIA; MANAGEMENT; LASIK; CXL;
D O I
10.4103/IJO.IJO_2557_22
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Purpose: Compare the safety and efficacy of wavefront-guided photorefractive keratotomy (PRK) 6 months after cross-linking (CXL) to wavefront-guided PRK alone for refractive correction in patients with bilateral asymmetric corneal topography. Methods: Prospective randomized clinical trial with 16 patients (32 eyes). CXL with subsequent PRK after 6 months in one eye, and PRK alone was performed in contralateral eyes. The follow-up was 10 years. We analyzed visual outcomes, Scheimpflug topography, and corneal haze evaluation. Results: Eyes in the PRK group showed better results than in the CXL + PRK group. Mean postoperative CDVA was 0.044 logmar (SD, 0.073) in the PRK group and 0.1 logmar (SD, 0.21) in the CXL + PRK group, the mean sphere was + 0.21 (SD, 0.6) D in the PRK group and 0.87 (SD, 2.3) D in the CXL + PRK group, and mean SE was -0.35 (SD, 0.65) D in the PRK group and 0.62 (SD, 2.32) D in the CXL + PRK group. In one patient, a steepening of 2.5 D and a thinning of 17 mu m occurred in PRK alone group. Two patients in the CXL + PRK group presented corneal haze. The overall complication rate was 18,75% (haze and ectasia). Conclusion: Non-simultaneous CXL and PRK procedures yielded good refractive results, but worse than those obtained with PRK alone. Although one patient in the PRK group developed corneal ectasia, the CXL + PRK group had a higher loss of vision lines, indicating less safety.
引用
收藏
页码:3210 / +
页数:14
相关论文
共 50 条
  • [41] Results of corneal collagen cross-linking in patients with corneal ectasia after laser refractive surgery-A prospective study
    Margines, J. Ben
    Rabinowitz, Yaron S.
    Li, Xiaohui
    Gaster, Ronald N.
    PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2023, 42
  • [42] Topographic corneal changes after collagen cross-linking in patients with corneal keratoconus
    Razmjoo, Hasan
    Nasrollahi, Alireza Peyman Kobra
    Salam, Hasan
    Karbasi, Najmeh
    Najarzadegan, Mohammad Reza
    JOURNAL OF RESEARCH IN MEDICAL SCIENCES, 2013, 18 (10): : 882 - 886
  • [43] Long-Term Comparison of Simultaneous Topography-Guided Photorefractive Keratectomy Followed by Corneal Cross-linking versus Corneal Cross-linking Alone
    Kontadakis, Georgios A.
    Kankariya, Vardhaman P.
    Tsoulnaras, Konstantinos
    Pallikaris, Aristofanis I.
    Plaka, Argyro
    Kymionis, George D.
    OPHTHALMOLOGY, 2016, 123 (05) : 974 - 983
  • [44] Corneal Epithelial Remodeling in a 6-Month Follow-up Period in Myopic Corneal Refractive Surgeries
    Zhu, ManMan
    Xin, Yue
    Vinciguerra, Riccardo
    Wang, Zheng
    Warsame, Abdullahi Mohamud
    Wang, Chong
    Zhu, DaTian
    Qu, ZhanXin
    Wang, Pu
    Zheng, XiaoBo
    Wang, JunJie
    Wang, QinMei
    Ye, YuFeng
    Chen, ShiHao
    Bao, FangJun
    Elsheikh, Ahmed
    JOURNAL OF REFRACTIVE SURGERY, 2023, 39 (03) : 187 - +
  • [45] Corneal collagen cross-linking with and without simultaneous intrastromal corneal ring segment implantation: One-year pilot study
    Sharma, Indra Prasad
    Bakshi, Ramendra
    Chaudhry, Monica
    EUROPEAN JOURNAL OF OPHTHALMOLOGY, 2021, 31 (01) : 61 - 68
  • [46] Epi-Off versus Epi-On Corneal Collagen Cross-Linking in Keratoconus Patients: A Comparative Study through 2-Year Follow-Up
    Cifariello, F.
    Minicucci, M.
    Di Renzo, F.
    Di Taranto, D.
    Coclite, G.
    Zaccaria, S.
    De Turris, S.
    Costagliola, C.
    JOURNAL OF OPHTHALMOLOGY, 2018, 2018
  • [47] Corneal collagen cross-linking in pediatric patients with keratoconus
    Stanojlovic, Svetlana
    Pejin, Vedrana
    Kalezic, Tanja
    Pantelic, Jelica
    Savic, Borivoje
    SRPSKI ARHIV ZA CELOKUPNO LEKARSTVO, 2020, 148 (1-2) : 70 - 75
  • [48] Corneal collagen cross-linking with riboflavin and ultraviolet-A light in progressive keratoconus. Results after 10-year follow-up
    Theuring, A.
    Spoerl, E.
    Pillunat, L. E.
    Raiskup, F.
    OPHTHALMOLOGE, 2015, 112 (02): : 140 - 147
  • [49] Simultaneous Transepithelial Topography-Guided Photorefractive Keratectomy and Accelerated Cross-Linking in Keratoconus: 2-Year Follow-Up
    Ahmet, Sibel
    Agca, Alper
    Yasa, Dilek
    Koc, Ahmet Alperen
    Togac, Mesut
    Yildirim, Yusuf
    Yildiz, Burcin Kepez
    Demirok, Ahmet
    BIOMED RESEARCH INTERNATIONAL, 2018, 2018
  • [50] Conventional and transepithelial corneal cross-linking for patients with keratoconus
    Zhang, Xiaoyu
    Zhao, Jing
    Li, Meiyan
    Tian, Mi
    Shen, Yang
    Zhou, Xingtao
    PLOS ONE, 2018, 13 (04):