Immunomodulatory role of decidual prolactin on the human fetal membranes and placenta

被引：10
作者：
Flores-Espinosa, Pilar [1 ]
Mendez, Isabel [2 ]
Irles, Claudine [3 ]
Olmos-Ortiz, Andrea [1 ]
Helguera-Repetto, Cecilia [1 ]
Mancilla-Herrera, Ismael [4 ]
Ortuno-Sahagun, Daniel [5 ]
Goffin, Vincent [6 ]
Zaga-Clavellina, Veronica [1 ]
机构：
[1] Inst Nacl Perinatol Isidro Espinosa Reyes, Dept Inmunobioquim, Mexico City, Mexico
[2] Univ Nacl Autonoma Mexico, Dept Neurobiol Celular & Mol, Inst Neurobiol, Campus UNAM Juriquilla, Juriquilla, Queretaro, Mexico
[3] Univ Sorbonne Paris Nord, Inst Natl Sante & Rech Med INSERM U978, Unite Format & Rech UFR Sante Med & Biol Humaine, Bobigny, France
[4] Inst Nacl Perinatol Isidro Espinosa Reyes, Dept Infectol & Inmunol, Mexico City, Mexico
[5] Univ Guadalajara, Lab Neuroinmunobiol Mol, Inst Invest Ciencias Biomed, Guadalajara, Mexico
[6] Univ Paris Cite, Inst Natl Sante & Rech Med INSERM, Inst Necker Enfants Malad, Unite Mixte Rech UMR S1151,CNRS,Unite Mixte Rech, Paris, France
来源：
FRONTIERS IN IMMUNOLOGY | 2023年 / 14卷
关键词：
immune privilege; decidual prolactin; pregnancy; maternal-fetal interface; fetal membranes; placenta; preterm labor; innate immunity; ENDOTHELIAL GROWTH-FACTOR; NECROSIS-FACTOR-ALPHA; MACROPHAGES IN-VITRO; AMNIOTIC-FLUID; DEVELOPMENTAL EXPRESSION; FETOMATERNAL INTERFACE; EXTRACELLULAR-MATRIX; TRANSCRIPTION FACTOR; PRETERM LABOR; RAT DECIDUA;
D O I：
10.3389/fimmu.2023.1212736
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The close interaction between fetal and maternal cells during pregnancy requires multiple immune-endocrine mechanisms to provide the fetus with a tolerogenic environment and protection against any infectious challenge. The fetal membranes and placenta create a hyperprolactinemic milieu in which prolactin (PRL) synthesized by the maternal decidua is transported through the amnion-chorion and accumulated into the amniotic cavity, where the fetus is bedded in high concentrations during pregnancy. PRL is a pleiotropic immune-neuroendocrine hormone with multiple immunomodulatory functions mainly related to reproduction. However, the biological role of PRL at the maternal-fetal interface has yet to be fully elucidated. In this review, we have summarized the current information on the multiple effects of PRL, focusing on its immunological effects and biological significance for the immune privilege of the maternal-fetal interface.
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页数：11
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共 118 条
[41]   Cervical and Amniotic Fluid Matrix Metalloproteinase-8 and Interleukin-6 Concentrations in Preterm Pregnancies with or without Preterm Premature Rupture of Membranes [J].
Holmstrom, Emilia ;
Myntti, Tarja ;
Sorsa, Timo ;
Kruit, Heidi ;
Juhila, Juuso ;
Paavonen, Jorma ;
Rahkonen, Leena ;
Stefanovic, Vedran .
FETAL DIAGNOSIS AND THERAPY, 2019, 46 (02) :103-110
[42]   Defective mammopoiesis, but normal hematopoiesis, in mice with a targeted disruption of the prolactin gene [J].
Horseman, ND ;
Zhao, WZ ;
Montecino-Rodriguez, E ;
Tanaka, M ;
Nakashima, K ;
Engle, SJ ;
Smith, F ;
Markoff, E ;
Dorshkind, K .
EMBO JOURNAL, 1997, 16 (23) :6926-6935
[43]   Risk factors associated with preterm labor, with special emphasis on preterm premature rupture of membranes and severe preterm labor [J].
Hosny, Alaa El-Dien M. S. ;
Fakhry, Mohsen N. ;
El-khayat, Waleed ;
Kashef, Mona T. .
JOURNAL OF THE CHINESE MEDICAL ASSOCIATION, 2020, 83 (03) :280-287
[44]   Serum prolactin levels across pregnancy and the establishment of reference intervals [J].
Hu, Yun ;
Ding, Yiling ;
Yang, Mengyuan ;
Xiang, Zhongyuan .
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2018, 56 (05) :838-842
[45]   Emerging role of toll-like receptors signaling and its regulators in preterm birth: a narrative review [J].
Huang, Ge ;
Yao, Dan ;
Yan, Xiaoli ;
Zheng, Mingyu ;
Yan, Ping ;
Chen, Xiaoxia ;
Wang, Dan .
ARCHIVES OF GYNECOLOGY AND OBSTETRICS, 2023, 308 (02) :319-339
[46]   TUMOR-NECROSIS-FACTOR-ALPHA INHIBITS THE SYNTHESIS AND RELEASE OF HUMAN DECIDUAL PROLACTIN [J].
JIKIHARA, H ;
HANDWERGER, S .
ENDOCRINOLOGY, 1994, 134 (01) :353-357
[47]   Localization and temporal expression of prolactin receptor in human endometrium [J].
Jones, RL ;
Critchley, HOD ;
Brooks, J ;
Jabbour, HN ;
McNeilly, AS .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1998, 83 (01) :258-262
[48]   Interleukin-2 inhibits the synthesis and release of prolactin from human decidual cells [J].
Kanda, Y ;
Jikihara, H ;
Markoff, E ;
Handwerger, S .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1999, 84 (02) :677-681
[49]   TGFβ1 Attenuates Expression of Prolactin and IGFBP-1 in Decidualized Endometrial Stromal Cells by Both SMAD-Dependent and SMAD-Independent Pathways [J].
Kane, Nicole M. ;
Jones, Marius ;
Brosens, Jan J. ;
Kelly, Rodney W. ;
Saunders, Philippa T. K. ;
Critchley, Hilary O. D. .
PLOS ONE, 2010, 5 (09)
[50]   Prolactin receptor gene transcriptional control, regulatory modalities relevant to breast cancer resistance and invasiveness [J].
Kavarthapu, Raghuveer ;
Dufau, Maria L. L. .
FRONTIERS IN ENDOCRINOLOGY, 2022, 13
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