Gene Therapy for Epilepsy: Clinical Studies are on the Road

被引：0

作者：

Mueller, Peter ^{[1
]}

Lerche, Holger ^{[1
]}

机构：

[1] Univ Tubingen, Hertie Inst Klin Hirnforsch, Abt Neurol Schwerpunkt Epileptol, Tubingen, Germany

来源：

FORTSCHRITTE DER NEUROLOGIE PSYCHIATRIE | 2023年 / 91卷 / 04期

关键词：

epilepsy; gene therapy; neurodevelopmental disorder; developmental and epileptic encephalopathy; Refractory focal epilepsy; NEUROPEPTIDE-Y; EXPRESSION;

D O I：

10.1055/a-1995-5405

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

For more than 10 years, research has been conducted on gene therapies for the most severe forms of epilepsy, which until now have proven resistant to treatment. First gene therapies are now in clinical trials for pharmacoresistant focal epilepsies and Dravet syndrome. In this article, we describe how these and many more gene therapies work and what they target.

引用

页码：135 / 140

页数：6

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