Tailoring micro/nano-fibers for biomedical applications

被引:102
作者
Kong, Bin [1 ]
Liu, Rui [1 ]
Guo, Jiahui [2 ,3 ]
Lu, Ling [2 ]
Zhou, Qing [1 ]
Zhao, Yuanjin [1 ,2 ,3 ,4 ]
机构
[1] Nanjing Univ, Nanjing Drum Tower Hosp, Affiliated Hosp, Med Sch,Dept Cardiothorac Surg,Inst Translat Med, Nanjing 210008, Peoples R China
[2] Nanjing Univ, Nanjing Drum Tower Hosp, Med Sch,Jiangsu Prov Key Med Discipline, Affiliated Hosp,Dept Otolaryngol Head & Neck Surg, Nanjing 210008, Peoples R China
[3] Southeast Univ, Sch Biol Sci & Med Engn, State Key Lab Bioelect, Nanjing 210096, Peoples R China
[4] Chinese Acad Sci, Inst Stem Cell & Regenerat, Beijing 100101, Peoples R China
基金
中国国家自然科学基金; 中国博士后科学基金;
关键词
Nano/micro fibers; Bioprinting; Electrospinning; Microfluidic spinning; Near field electrospinning; Biomedical field; DRUG-DELIVERY; SILK FIBERS; STEM-CELLS; ALGINATE MICROFIBERS; ELECTROSPUN FIBERS; HOLLOW MICROFIBERS; TISSUE; FABRICATION; NANOFIBERS; SCAFFOLDS;
D O I
10.1016/j.bioactmat.2022.04.016
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Nano/micro fibers have evoked much attention of scientists and have been researched as cutting edge and hotspot in the area of fiber science in recent years due to the rapid development of various advanced manufacturing technologies, and the appearance of fascinating and special functions and properties, such as the enhanced mechanical strength, high surface area to volume ratio and special functionalities shown in the surface, triggered by the nano or micro-scale dimensions. In addition, these outstanding and special characteristics of the nano/micro fibers impart fiber-based materials with wide applications, such as environmental engineering, electronic and biomedical fields. This review mainly focuses on the recent development in the various nano/micro fibers fabrication strategies and corresponding applications in the biomedical fields, including tissue engineering scaffolds, drug delivery, wound healing, and biosensors. Moreover, the challenges for the fabrications and applications and future perspectives are presented.
引用
收藏
页码:328 / 347
页数:20
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