Therapeutic approaches for chronic hepatitis C: a concise review

被引：3

作者：

Nawaz, Allah ^{[1
,2
,10
]}

Manzoor, Azhar ^{[3
]}

Ahmed, Saeed ^{[4
]}

Ahmed, Naveed ^{[5
]}

Abbas, Waseem ^{[2
]}

Mir, Mushtaq Ahmad ^{[6
]}

Bilal, Muhammad ^{[7
]}

Sheikh, Alisha ^{[8
]}

Ahmad, Saleem ^{[9
]}

Jeelani, Ishtiaq ^{[2
,11
]}

Nakagawa, Takashi ^{[2
]}

机构：

[1] Harvard Med Sch, Joslin Diabet Ctr, Boston, MA 02115 USA

[2] Univ Toyama, Fac Med, Dept Mol & Med Pharmacol, Toyama, Japan

[3] Bahawal Victoria Hosp, Dept Surg, Bahawalpur, Pakistan

[4] Rawalpindi Med Univ, Dept Med & Surg, Rawalpindi, Punjab, Pakistan

[5] Univ Poonch Rawalakot, Dept Pharm, Rawalakot, Azad Jammu & Ka, Pakistan

[6] King Khalid Univ, Coll Appl Med Sci, Dept Clin Lab Sci, Abha, Saudi Arabia

[7] Univ Toyama, Fac Med, Dept Internal Med 1, Toyama, Japan

[8] Univ Jammu, Jammu Inst Ayurveda & Res, Jammu, India

[9] Louisiana State Univ, Hlth Sci Ctr, Cardiovasc Ctr Excellence, New Orleans, LA USA

[10] Harvard Univ, Joslin Diabet Ctr, Harvard Med Sch, Boston, MA 02115 USA

[11] Univ Calif San Diego, Dept Med, Div Endocrinol & Metab, San Diego, CA 92093 USA

来源：

FRONTIERS IN PHARMACOLOGY | 2024年 / 14卷

关键词：

hepatitis C virus; direct-acting antiviral agents (DAAs); botanical drugs; hepatitis C; hepatoprotective and antiviral properties of medicinal plants; VIRUS-INFECTION; NATURAL COMPOUNDS; INTERFERON-ALPHA-2B; HCV; SILYMARIN; INHIBITION; RIBAVIRIN; CIRRHOSIS; TRIAL; REPLICATION;

D O I：

10.3389/fphar.2023.1334160

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Hepatitis C virus (HCV) infection is a significant global health concern, prompting the need for effective treatment strategies. This in-depth review critically assesses the landscape of HCV treatment, drawing parallels between traditional interferon/ribavirin therapy historically pivotal in HCV management and herbal approaches rooted in traditional and complementary medicine. Advancements in therapeutic development and enhanced clinical outcomes axis on a comprehensive understanding of the diverse HCV genome, its natural variations, pathogenesis, and the impact of dietary, social, environmental, and economic factors. A thorough analysis was conducted through reputable sources such as Science Direct, PubMed, Scopus, Web of Science, books, and dissertations. This review primarily focuses on the intricate nature of HCV genomes and explores the potential of botanical drugs in both preventing and treating HCV infections.

引用

页数：8

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