Editorial: The Application of Proteogenomics to Urine Analysis for the Identification of Novel Biomarkers of Prostate Cancer: An Exploratory Study

被引:0
|
作者
Gamallat, Yaser [1 ,2 ]
Bismar, Tarek A. [1 ,2 ,3 ,4 ,5 ]
机构
[1] Univ Calgary, Arnie Charbonneau Canc Inst, Cumming Sch Med, Dept Pathol & Lab Med, Calgary, AB T2N 4N1, Canada
[2] Univ Calgary, Arnie Charbonneau Canc Inst, Cumming Sch Med, Dept Oncol Biochem & Mol Biol, Calgary, AB T2N 4N1, Canada
[3] Rockyview Gen Hosp, Dept Pathol, Alberta Precis Labs, Calgary, AB T2V 1P9, Canada
[4] Rockyview Gen Hosp, Dept Lab Med, Alberta Precis Labs, Calgary, AB T2V 1P9, Canada
[5] Rockyview Gen Hosp, Prostate Canc Ctr, Calgary, AB T2V 1P9, Canada
关键词
proteogenomics; prostate cancer; biomarker detection;
D O I
10.3390/cancers15164143
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
In this editorial context, we aim to leverage the potential of proteogenomics, which integrates genomic and proteomic data, to discover novel biomarkers that can aid in the diagnosis and management of prostate cancer. We highlight the importance of proteogenomics for understanding the functional consequences of somatic mutations in cancer and demonstrating how proteogenomic analysis can provide insights into the effects of genetic alterations on the proteomic landscape and identify potential therapeutic targets. This article also emphasizes the potential of urine analysis for the detection of prostate cancer. Overall, our editorial paper provides general insights on the application of proteogenomics to urine analysis for the identification of novel biomarkers of prostate cancer.
引用
收藏
页数:5
相关论文
共 50 条
  • [31] Identification of the novel therapeutic targets and biomarkers associated of prostate cancer with cancer-associated fibroblasts (CAFs)
    Zhai, Xinyu
    Chen, Xinglin
    Wan, Zhong
    Ge, Minyao
    Ding, Yi
    Gu, Jianyi
    Hua, Jinjun
    Guo, Dongdong
    Tan, Mingyue
    Xu, Dongliang
    FRONTIERS IN ONCOLOGY, 2023, 13
  • [32] miRNAs as novel biomarkers in the management of prostate cancer
    Filella, Xavier
    Foj, Laura
    CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2017, 55 (05) : 715 - 736
  • [33] Prostate cancer: Novel genetic and immunologic biomarkers
    Samare-Najaf, Mohammad
    Kouchaki, Hosein
    Mahini, Seyed Moein
    Rounkian, Masoumeh Saberi
    Tavakoli, Yasaman
    Samareh, Ali
    Azadbakht, Mohammad Karim
    Jamali, Navid
    CLINICA CHIMICA ACTA, 2024, 555
  • [34] A Panel of MicroRNAs as Diagnostic Biomarkers for the Identification of Prostate Cancer
    Daniel, Rhonda
    Wu, Qianni
    Williams, Vernell
    Clark, Gene
    Guruli, Georgi
    Zehner, Zendra
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (06)
  • [35] The Identification of Potential Biomarkers and Biological Pathways in Prostate Cancer
    Song, Zhengshuai
    Huang, Yu
    Zhao, Ye
    Ruan, Hailong
    Yang, Hongmei
    Cao, Qi
    Liu, Di
    Zhang, Xiaoping
    Chen, Ke
    JOURNAL OF CANCER, 2019, 10 (06): : 1398 - 1408
  • [36] Identification of potential diagnostic and prognostic biomarkers for prostate cancer
    Zhang, Qiang
    Yin, Xiujuan
    Pan, Zhiwei
    Cao, Yingying
    Han, Shaojie
    Gao, Guojun
    Gao, Zhiqin
    Pan, Zhifang
    Feng, Weiguo
    ONCOLOGY LETTERS, 2019, 18 (04) : 4237 - 4245
  • [37] RNA biomarkers to facilitate the identification of aggressive prostate cancer
    Pellegrini, Kathryn L.
    Sanda, Martin G.
    Moreno, Carlos S.
    MOLECULAR ASPECTS OF MEDICINE, 2015, 45 : 37 - 46
  • [38] Identification of docetaxel-related biomarkers for prostate cancer
    Peng, Yun
    Dong, Shiqiang
    Yang, Zhikai
    Song, Yuxuan
    Ding, Jin
    Hou, Dingkun
    Wang, Lili
    Zhang, Zheyu
    Li, Nan
    Wang, Haitao
    ANDROLOGIA, 2021, 53 (07)
  • [39] Use of a combination of biomarkers in serum and urine to improve detection of prostate cancer
    Prior, Celia
    Guillen-Grima, Francisco
    Robles, Jose E.
    Rosell, David
    Fernandez-Montero, Jose M.
    Agirre, Xabier
    Catena, Raul
    Calvo, Alfonso
    WORLD JOURNAL OF UROLOGY, 2010, 28 (06) : 681 - 686
  • [40] Use of a combination of biomarkers in serum and urine to improve detection of prostate cancer
    Celia Prior
    Francisco Guillen-Grima
    Jose E. Robles
    David Rosell
    Jose M. Fernandez-Montero
    Xabier Agirre
    Raúl Catena
    Alfonso Calvo
    World Journal of Urology, 2010, 28 : 681 - 686