Editorial: The Application of Proteogenomics to Urine Analysis for the Identification of Novel Biomarkers of Prostate Cancer: An Exploratory Study

被引：0
|
作者：
Gamallat, Yaser [1 ,2 ]
Bismar, Tarek A. [1 ,2 ,3 ,4 ,5 ]
机构：
[1] Univ Calgary, Arnie Charbonneau Canc Inst, Cumming Sch Med, Dept Pathol & Lab Med, Calgary, AB T2N 4N1, Canada
[2] Univ Calgary, Arnie Charbonneau Canc Inst, Cumming Sch Med, Dept Oncol Biochem & Mol Biol, Calgary, AB T2N 4N1, Canada
[3] Rockyview Gen Hosp, Dept Pathol, Alberta Precis Labs, Calgary, AB T2V 1P9, Canada
[4] Rockyview Gen Hosp, Dept Lab Med, Alberta Precis Labs, Calgary, AB T2V 1P9, Canada
[5] Rockyview Gen Hosp, Prostate Canc Ctr, Calgary, AB T2V 1P9, Canada
来源：
CANCERS | 2023年 / 15卷 / 16期
关键词：
proteogenomics; prostate cancer; biomarker detection;
D O I：
10.3390/cancers15164143
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
In this editorial context, we aim to leverage the potential of proteogenomics, which integrates genomic and proteomic data, to discover novel biomarkers that can aid in the diagnosis and management of prostate cancer. We highlight the importance of proteogenomics for understanding the functional consequences of somatic mutations in cancer and demonstrating how proteogenomic analysis can provide insights into the effects of genetic alterations on the proteomic landscape and identify potential therapeutic targets. This article also emphasizes the potential of urine analysis for the detection of prostate cancer. Overall, our editorial paper provides general insights on the application of proteogenomics to urine analysis for the identification of novel biomarkers of prostate cancer.
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收藏
页数：5
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