The Effect of Advanced Platelet-Rich Fibrin in Tissue Regeneration in Reconstructive and Graft Surgery: Systematic Review

被引：8

作者：

Pereira, Vinicius Balan Santos ^{[1
,3
]}

Barbirato, Davi da Silva ^{[1
]}

Lago, Carlos Augusto Pereira do ^{[1
]}

Vasconcelos, Belmiro Cavalcanti do Egito ^{[1
,2
]}

机构：

[1] Univ Pernambuco, Oral & Maxillofacial Surg, Recife, PE, Brazil

[2] Hosp Restauracao, Oral & Maxillofacial Surg, Recife, PE, Brazil

[3] Univ Pernambuco, Dent Sch, Div Oral & Maxillofacial Surg, Arnobio Marques St,310, BR-50100130 Recife, PE, Brazil

来源：

JOURNAL OF CRANIOFACIAL SURGERY | 2023年 / 34卷 / 04期

关键词：

Bone grafting; bone regeneration; guided tissue regeneration; platelet-rich fibrin; wound healing; RIDGE PRESERVATION; SOCKET PRESERVATION; TOOTH EXTRACTION; AGREEMENT; PRF; COEFFICIENT; MANAGEMENT; LEUKOCYTE; RELEASE;

D O I：

10.1097/SCS.0000000000009328

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

This systematic review answered the guiding question using the PICO system: "What are the effects of advanced platelet-rich fibrin (A-PRF) on alveolar ridge preservation and tissue gain in reconstructive and jaw graft surgery?" Searches were performed in the PubMed|MEDLINE, Scopus, Embase, Web of Science, Cochrane Library, and LILACS|bvs databases. In total, 573 articles were found in the initial search, and 564 were evaluated after the removal of duplicates, of which 5 randomized controlled trials met the eligibility criteria and were included 2 studies investigated the effect of A-PRF on the preservation of the bone ridge, 1 study evaluated the tissue repair after tooth extraction with A-PRF, 1 evaluated the peri-implant gap filling with A-PRF-xenograft mixture, and other the A-PRF on the treatment of alveolar osteitis. Advanced-PRF preparation protocol varied between the included studies from 8 to 13 minutes of centrifugation, at 1300 RPM (200g). The use of A-PRF provided greater dimensions of height and more favorable maintenance of the ridge profile, probing depth, and gingival margin level after extraction. Advanced-PRF also increased bone density, vital bone, epithelial healing, and control of postoperative pain and swelling after tooth extraction and in the treatment of alveolar osteitis.

引用

页码：1217 / 1221

页数：5