Role of bioactive peptides derived from food proteins in programmed cell death to treat inflammatory diseases and cancer

被引:10
|
作者
Deng, Zhao [1 ,2 ]
Yang, Zhipeng [1 ]
Peng, Jian [1 ,3 ]
机构
[1] Huazhong Agr Univ, Dept Anim Nutr & Feed Sci, Coll Anim Sci & Technol, Wuhan, Peoples R China
[2] Chinese Acad Sci, State Key Lab Mol Dev Biol, Inst Genet & Dev Biol, Beijing, Peoples R China
[3] Cooperat Innovat Ctr Sustainable Pig Prod, Wuhan, Hubei, Peoples R China
基金
中国国家自然科学基金;
关键词
Bioactive peptides; programmed cell death; inflammatory diseases; cancer; apoptosis; autophagy; necroptosis; pyroptosis; ferroptosis; INDUCED OXIDATIVE STRESS; FISH SKIN GELATIN; NLRP3; INFLAMMASOME; ANTIOXIDATIVE PEPTIDES; AUTOPHAGY INDUCTION; BOWEL-DISEASE; MOUSE MODEL; APOPTOSIS; ACTIVATION; GLIOBLASTOMA;
D O I
10.1080/10408398.2021.1992606
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Bioactive peptides are specific peptide which usually contains 2-20 amino acid residues and actively exerts various functions and biological activities and ultimately affect health. Programmed cell deaths are some styles of cell death discovered in recent years, which is the key to tissue development and balance, eliminating excess, damaged or aging cells. More importantly, programmed cell death is a potential way to treat inflammatory diseases and cancer. In this review, through screening references from 2015 to present, we introduce the effect of bioactive peptides derived from food proteins on inflammatory diseases or cancer through regulating programmed cell deaths, including apoptosis, autophagy, pyroptosis, ferroptosis, and necroptosis. And this review also introduces the targets of these bioactive peptides to regulate programmed cell death. The purpose of this review is to help to expand the prospective applications of bioactive peptides in the field of inflammatory disease and cancer to provide some guidance.
引用
收藏
页码:3664 / 3682
页数:19
相关论文
共 50 条
  • [41] Bioactive peptides derived from bovine whey proteins:: opioid and ace-inhibitory peptides
    Pihlanto-Leppälä, A
    TRENDS IN FOOD SCIENCE & TECHNOLOGY, 2000, 11 (9-10) : 347 - 356
  • [42] The role of exosomes in cancer-related programmed cell death
    Li, Xin
    Jing, Zuoqian
    Li, Xuejie
    Liu, Lei
    Xiao, Xiang
    Zhong, Yifan
    Ren, Zihan
    IMMUNOLOGICAL REVIEWS, 2024, 321 (01) : 169 - 180
  • [43] Effect of food derived bioactive peptides on gut health and inflammatory mediators in vivo: a systematic review
    Mishima, Marcella Duarte Villas
    Martino, Hercia Stampini Duarte
    Meneguelli, Talitha Silva
    Tako, Elad
    CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION, 2024, 64 (32) : 11974 - 11984
  • [44] Programmed Cell Death, from a Cancer Perspective: An Overview
    Mishra, Abhay P.
    Salehi, Bahare
    Sharifi-Rad, Mehdi
    Pezzani, Raffaele
    Kobarfard, Farzad
    Sharifi-Rad, Javad
    Nigam, Manisha
    MOLECULAR DIAGNOSIS & THERAPY, 2018, 22 (03) : 281 - 295
  • [45] From agrifood waste to functional foods: the role of food by-products-derived bioactive peptides in antioxidant and anti-inflammatory signalling pathway activation
    Tonolo, Federica
    Rigobello, Maria Pia
    Vianello, Fabio
    JOURNAL OF PEPTIDE SCIENCE, 2024, 30
  • [46] Programmed Cell Death, from a Cancer Perspective: An Overview
    Abhay P. Mishra
    Bahare Salehi
    Mehdi Sharifi-Rad
    Raffaele Pezzani
    Farzad Kobarfard
    Javad Sharifi-Rad
    Manisha Nigam
    Molecular Diagnosis & Therapy, 2018, 22 : 281 - 295
  • [47] The role of programmed cell death as an emerging new concept for the pathogenesis of autoimmune diseases
    Mountz, JD
    Zhou, T
    Su, X
    Wu, JG
    Cheng, JH
    CLINICAL IMMUNOLOGY AND IMMUNOPATHOLOGY, 1996, 80 (03): : S2 - S14
  • [48] Role of programmed cell death 4 in diseases: a double-edged sword
    Jiang, Yang
    Jia, Yufeng
    Zhang, Lining
    CELLULAR & MOLECULAR IMMUNOLOGY, 2017, 14 (11) : 884 - 886
  • [49] Bioactive peptides derived from milk proteins and their health beneficial potentials: an update
    Nagpal, Ravinder
    Behare, Pradip
    Rana, Rajiv
    Kumar, Ashwani
    Kumar, Manoj
    Arora, Sanu
    Morotta, Fransesco
    Jain, Shalini
    Yadav, Hariom
    FOOD & FUNCTION, 2011, 2 (01) : 18 - 27
  • [50] The Emerging Role of m6A and Programmed Cell Death in Cardiovascular Diseases
    Wang, Haixia
    Han, Juanjuan
    Kong, Hui
    Ma, Ce
    Zhang, Xin-an
    BIOMOLECULES, 2025, 15 (02)