Role of bioactive peptides derived from food proteins in programmed cell death to treat inflammatory diseases and cancer

被引:10
|
作者
Deng, Zhao [1 ,2 ]
Yang, Zhipeng [1 ]
Peng, Jian [1 ,3 ]
机构
[1] Huazhong Agr Univ, Dept Anim Nutr & Feed Sci, Coll Anim Sci & Technol, Wuhan, Peoples R China
[2] Chinese Acad Sci, State Key Lab Mol Dev Biol, Inst Genet & Dev Biol, Beijing, Peoples R China
[3] Cooperat Innovat Ctr Sustainable Pig Prod, Wuhan, Hubei, Peoples R China
基金
中国国家自然科学基金;
关键词
Bioactive peptides; programmed cell death; inflammatory diseases; cancer; apoptosis; autophagy; necroptosis; pyroptosis; ferroptosis; INDUCED OXIDATIVE STRESS; FISH SKIN GELATIN; NLRP3; INFLAMMASOME; ANTIOXIDATIVE PEPTIDES; AUTOPHAGY INDUCTION; BOWEL-DISEASE; MOUSE MODEL; APOPTOSIS; ACTIVATION; GLIOBLASTOMA;
D O I
10.1080/10408398.2021.1992606
中图分类号
TS2 [食品工业];
学科分类号
0832 ;
摘要
Bioactive peptides are specific peptide which usually contains 2-20 amino acid residues and actively exerts various functions and biological activities and ultimately affect health. Programmed cell deaths are some styles of cell death discovered in recent years, which is the key to tissue development and balance, eliminating excess, damaged or aging cells. More importantly, programmed cell death is a potential way to treat inflammatory diseases and cancer. In this review, through screening references from 2015 to present, we introduce the effect of bioactive peptides derived from food proteins on inflammatory diseases or cancer through regulating programmed cell deaths, including apoptosis, autophagy, pyroptosis, ferroptosis, and necroptosis. And this review also introduces the targets of these bioactive peptides to regulate programmed cell death. The purpose of this review is to help to expand the prospective applications of bioactive peptides in the field of inflammatory disease and cancer to provide some guidance.
引用
收藏
页码:3664 / 3682
页数:19
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