Clinical impact of human parainfluenza virus infections before and during the COVID-19 pandemic in Southern China

被引：5

作者：

Li, Ya ^{[1
]}

Liang, Ying ^{[1
]}

Tang, Jiaqi ^{[1
]}

Li, Ning ^{[1
]}

Yang, Yihao ^{[1
]}

Guo, Wenyu ^{[1
]}

Lin, Cheng ^{[1
]}

Wu, Jinyu ^{[1
]}

Lin, Yongping ^{[1
,2
,3
]}

Chen, Qigao ^{[1
,2
]}

机构：

[1] Guangzhou Med Univ, Affiliated Hosp 1, Dept Lab Med, Guangzhou, Peoples R China

[2] Guangzhou Med Univ, KingMed Sch Lab Med, Guangzhou, Peoples R China

[3] Chinese Acad Med Sci, Shenzhen Ctr, Dept Lab Med, Canc Hosp, Shenzhen, Peoples R China

来源：

MICROBES AND INFECTION | 2023年 / 25卷 / 08期

关键词：

Human parainfluenza virus; Epidemiology; Hospitalization; COVID-19; RESPIRATORY-TRACT INFECTIONS; SYNCYTIAL VIRUS; CHILDREN;

D O I：

10.1016/j.micinf.2023.105219

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Human parainfluenza viruses (HPIVs) are a leading cause of acute respiratory tract infections (ARTIs). Non-pharmaceutical interventions (NPIs) were widely administered to combat the pandemic of the coronavirus disease 2019 (COVID-19). Respiratory specimens were obtained from 10,454 hospitalized children with ARTIs to detect HPIV. We investigated differences in epidemiological and clinical characteristics of HPIV infections before (2017-2019) and during the COVID-19 pandemic (2020-2022). HPIVs were detected in 392 (3.75%, 392/10,454) patients, of whom 70 (17.86%), 48 (12.24%), and 274 (69.90%) were positive for HPIV1, HPIV2, and HPIV3, respectively. Detection rates of HPIV3 were higher in 2020 -2022 than in 2017-2019 (3.38% vs. 2.24%). The seasonal distribution of HPIV1 showed no difference, but HPIV3 peaked between September and December during the COVID-19 pandemic, which differed from previous epidemiological patterns. Compared to the period before the COVID-19 pandemic, there has been a noticeable decrease in the incidence of asthma, moist rales, and emesis in patients infected with HPIV1 and in asthma, expectoration, and severe pneumonia in patients infected with HPIV3 during 2020-2022. The detection rates of HPIV increased in Southern China during the COVID-19 outbreak, which underlines the importance of continuous surveillance of HPIV in the next epidemic season. (c) 2023 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

引用

页数：7