Chromophobe Renal Cell Carcinoma with Sarcomatoid Differentiation

被引：1
作者：
Lichtbroun, Benjamin J. [1 ,2 ]
Shinder, Brian [1 ,2 ]
Sara, Tina Gowda [1 ,2 ]
Srivastava, Arnav [1 ,2 ]
Saraiya, Biren [2 ,3 ]
Mayer, Tina M. [2 ,3 ]
Cristelli, Ryan [2 ,4 ]
Sadimin, Evita [2 ,4 ]
Weiss, Robert E. [1 ,2 ]
Singer, Eric A. [1 ,2 ,5 ]
机构：
[1] Rutgers Canc Inst New Jersey, Dept Surg, Sect Urol Oncol, New Brunswick, NJ USA
[2] Rutgers Robert Wood Johnson Med Sch, New Brunswick, NJ USA
[3] Rutgers Canc Inst New Jersey, Dept Med, Div Med Oncol, New Brunswick, NJ USA
[4] Rutgers Canc Inst New Jersey, Dept Pathol, Div Urol Pathol, New Brunswick, NJ USA
[5] Rutgers Canc Inst New Jersey, Sect Urol Oncol, 195 Little Albany St Room 4563, New Brunswick, NJ 08901 USA
来源：
JOURNAL OF KIDNEY CANCER AND VHL | 2023年 / 10卷 / 03期
关键词：
chromophobe renal cell carcinoma; immune checkpoint inhibitors; kidney cancer; sarcomatoid; FEATURES; COMBINATION;
D O I：
10.15586/jkcvhl.v10i3.254
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Chromophobe renal cell carcinoma (chRCC) is one of the less common types of kidney cancer and generally portends a more favorable prognosis. RCC with sarcomatoid differentiation has a more aggressive clinical course with poor outcomes. Four cases of chRCC with varying degrees of sarcomatoid differentiation were retrospectively reviewed at our institution, and clinicopathologic data as well as clinical courses were reported. Patients with higher degrees of sarcomatoid differentiation and larger tumors at presentation generally had and worse overall survival. chRCC with sarcomatoid differentiation portends a poor prognosis with limited data on systemic treatment options for metastatic disease.
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页码：1 / 8
页数：8
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