BRCA, infertility, and fertility preservation: a review for counseling

被引：1

作者：

Baltaci, Ege ^{[1
]}

Kazanci, Ferah ^{[2
]}

Sahin, Feride Iffet ^{[1
]}

机构：

[1] Baskent Univ Hosp, Dept Med Genet, Ankara, Turkiye

[2] Nezip Fazil City Hosp, Dept Gynecol & Obstet, Kahramanmaras, Turkiye

来源：

JOURNAL OF ASSISTED REPRODUCTION AND GENETICS | 2023年 / 40卷 / 03期

关键词：

BRCA1; BRCA2; Infertility; Fertility preservation; Breast cancer; Genetic counseling; BREAST-CANCER; MUTATION CARRIERS; OVARIAN RESERVE; WOMEN; ASSOCIATION; INCREASE; OUTCOMES; OOCYTES; ISSUES; AMH;

D O I：

10.1007/s10815-023-02725-y

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

BRCA mutations as a triggering factor in breast cancer have been reported to result in fertility problems and oocyte aging in young patients with cancer diagnosis. These patients are concerned about fertility problems and family planning before undergoing treatment modalities that may result in infertility. In this review, we conducted analysis of the literature on the association between BRCA mutations and infertility, possible fertility preservation options, and their safety and tried to gather results from different disciplines and points of view on the matter. Our aim is to provide a general summary of recent studies to provide further insight on the matter for counseling BRCA mutation carriers on fertility preservation methods and their implications.

引用

页码：465 / 472

页数：8

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