The multifaceted role of extracellular ATP in sperm function: From spermatogenesis to fertilization

被引：2
|
作者：
Cao, Heran [1 ]
Li, Long [1 ]
Liu, Shujuan [1 ]
Wang, Yang [1 ]
Liu, Xianglin [2 ]
Yang, Fangxia [2 ]
Dong, Wuzi [1 ,3 ]
机构：
[1] Northwest A&F Univ, Coll Anim Sci & Technol, Yangling 712100, Shaanxi, Peoples R China
[2] Northwest A&F Univ, Coll Forestry, Yangling 712100, Shaanxi, Peoples R China
[3] 22 Xinong Rd, Yangling 712100, Peoples R China
来源：
THERIOGENOLOGY | 2024年 / 214卷
关键词：
Extracellular ATP; Sperm; Sperm function; Male infertility; RAT SERTOLI-CELLS; PURINERGIC SIGNALING PATHWAYS; TESTICULAR PERITUBULAR CELLS; FOLLICLE-STIMULATING-HORMONE; MALE REPRODUCTIVE-TRACT; ADENOSINE-TRIPHOSPHATE; IN-VITRO; P2-PURINERGIC RECEPTORS; INTRACELLULAR CALCIUM; ENERGY-METABOLISM;
D O I：
10.1016/j.theriogenology.2023.10.019
中图分类号：
Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
Extracellular adenosine 5 '-triphosphate (ATP) is a vital signaling molecule involved in various physiological processes within the body. In recent years, studies have revealed its significant role in male reproduction, particularly in sperm function. This review explores the multifaceted role of extracellular ATP in sperm function, from spermatogenesis to fertilization. We discuss the impact of extracellular ATP on spermatogenesis, sperm maturation and sperm-egg fusion, highlighting the complex regulatory mechanisms and potential clinical applications in the context of male infertility. By examining the latest research, we emphasize the crucial role of extracellular ATP in sperm function and propose future research directions to further.
引用
收藏
页码：98 / 106
页数：9
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