Applications of machine learning in familial hypercholesterolemia

被引:5
作者
Luo, Ren-Fei [1 ]
Wang, Jing-Hui [1 ,2 ]
Hu, Li-Juan [3 ]
Fu, Qing-An [1 ]
Zhang, Si-Yi [2 ]
Jiang, Long [1 ]
机构
[1] Nanchang Univ, Dept Cardiovasc Med, Affiliated Hosp 2, Nanchang, Peoples R China
[2] Nanchang Univ, Dept Clin Med, Queen Mary Sch, Nanchang, Peoples R China
[3] Nanchang Med Coll, Dept Nursing, Nanchang, Peoples R China
来源
FRONTIERS IN CARDIOVASCULAR MEDICINE | 2023年 / 10卷
关键词
familial hypercholesterolemia; machine learning; screening; diagnosis; risk assessment; ARTIFICIAL-INTELLIGENCE; GUIDANCE; RISK; VALIDATION; GUIDELINES; CLINICIAN; UNIVERSAL; DISEASE; CARE;
D O I
10.3389/fcvm.2023.1237258
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Familial hypercholesterolemia (FH) is a common hereditary cholesterol metabolic disease that usually leads to an increase in the level of low-density lipoprotein cholesterol in plasma and an increase in the risk of cardiovascular disease. The lack of disease screening and diagnosis often results in FH patients being unable to receive early intervention and treatment, which may mean early occurrence of cardiovascular disease. Thus, more requirements for FH identification and management have been proposed. Recently, machine learning (ML) has made great progress in the field of medicine, including many innovative applications in cardiovascular medicine. In this review, we discussed how ML can be used for FH screening, diagnosis and risk assessment based on different data sources, such as electronic health records, plasma lipid profiles and corneal radian images. In the future, research aimed at developing ML models with better performance and accuracy will continue to overcome the limitations of ML, provide better prediction, diagnosis and management tools for FH, and ultimately achieve the goal of early diagnosis and treatment of FH.
引用
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页数:9
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