Lipid-Lowering Nutraceuticals for an Integrative Approach to Dyslipidemia

被引：6
作者：
Cheung, Brian [1 ,2 ]
Sikand, Geeta [2 ]
Dineen, Elizabeth H. [1 ,2 ]
Malik, Shaista [1 ,2 ]
El-Farra, Ailin Barseghian [1 ,2 ]
机构：
[1] Susan Samueli Integrat Hlth Inst, 856 Hlth Sci Rd, Irvine, CA 92617 USA
[2] Univ Calif Irvine, Div Cardiol, Irvine, CA 92521 USA
来源：
JOURNAL OF CLINICAL MEDICINE | 2023年 / 12卷 / 10期
关键词：
apolipoprotein B; atherosclerosis; cardiometabolic; cardiovascular disease; cardiovascular risk reduction; complementary medicine; integrative medicine; lipoprotein (a); LOW-DENSITY-LIPOPROTEIN; RANDOMIZED DOUBLE-BLIND; LINOLEIC-ACID SUPPLEMENTATION; NON-HDL CHOLESTEROL; HIGH-FAT DIET; METABOLIC SYNDROME; LDL CHOLESTEROL; GENE-EXPRESSION; L-CARNITINE; CHROMIUM SUPPLEMENTATION;
D O I：
10.3390/jcm12103414
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Dyslipidemia is a treatable risk factor for atherosclerotic cardiovascular disease that can be addressed through lifestyle changes and/or lipid-lowering therapies. Adherence to statins can be a clinical challenge in some patients due to statin-associated muscle symptoms and other side effects. There is a growing interest in integrative cardiology and nutraceuticals in the management of dyslipidemia, as some patients desire or are actively seeking a more natural approach. These agents have been used in patients with and without established atherosclerotic cardiovascular disease. We provide an updated review of the evidence on many new and emerging nutraceuticals. We describe the mechanism of action, lipid-lowering effects, and side effects of many nutraceuticals, including red yeast rice, bergamot and others.
引用
收藏
页数：39
相关论文
共 194 条
  • [21] Coenzyme Q10 supplementation: Efficacy, safety, and formulation challenges
    Arenas-Jal, Marta
    Sune-Negre, J. M.
    Garcia-Montoya, Encarna
    [J]. COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY, 2020, 19 (02) : 574 - 594
  • [22] Arnett DK, 2019, CIRCULATION, V140, pE563, DOI [10.1161/CIR.0000000000000677, 10.1161/CIR.0000000000000678, 10.1016/j.jacc.2019.03.009, 10.1016/j.jacc.2019.03.010]
  • [23] Effects of chromium supplementation on lipid profile in patients with type 2 diabetes: A systematic review and dose-response meta-analysis of randomized controlled trials
    Asbaghi, Omid
    Naeini, Fatemeh
    Ashtary-Larky, Damoon
    Moradi, Sajjad
    Zakeri, Nazanin
    Eslampour, Elham
    Kelishadi, Mahnaz Rezaei
    Naeini, Amirmansour Alavi
    [J]. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY, 2021, 66
  • [24] The Effects of Magnesium Supplementation on Lipid Profile Among Type 2 Diabetes Patients: a Systematic Review and Meta-analysis of Randomized Controlled Trials
    Asbaghi, Omid
    Moradi, Sajjad
    Nezamoleslami, Shokufeh
    Moosavian, Seyedeh Parisa
    Kermani, Mohammad Ali Hojjati
    Lazaridi, Anastasia Viktoria
    Miraghajani, Maryam
    [J]. BIOLOGICAL TRACE ELEMENT RESEARCH, 2021, 199 (03) : 861 - 873
  • [25] Ameliorative effects of Nigella sativa on dyslipidemia
    Asgary, S.
    Sahebkar, A.
    Goli-malekabadi, N.
    [J]. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION, 2015, 38 (10) : 1039 - 1046
  • [26] Efficacy of L-carnitine supplementation for management of blood lipids: A systematic review and dose-response meta-analysis of randomized controlled trials
    Askarpour, Moein
    Hadi, Amir
    Symonds, Michael E.
    Miraghajani, Maryam
    Sheikhi, Ali
    Sadeghi, Omid
    Ghaedi, Ehsan
    [J]. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES, 2019, 29 (11) : 1151 - 1167
  • [27] Lupin protein positively affects plasma LDL cholesterol and LDL:HDL cholesterol ratio in hypercholesterolemic adults after four weeks of supplementation: a randomized, controlled crossover study
    Baehr, Melanie
    Fechner, Anita
    Kraemer, Julia
    Kiehntopf, Michael
    Jahreis, Gerhard
    [J]. NUTRITION JOURNAL, 2013, 12
  • [28] Red yeast rice for dyslipidaemias and cardiovascular risk reduction: A position paper of the International Lipid Expert Panel
    Banach, Maciej
    Catapano, Alberico L.
    Cicero, Arrigo F. G.
    Escobar, Carlos
    Foger, Bernhard
    Katsiki, Niki
    Latkovskis, Gustavs
    Rakowski, Michal
    Reiner, Zeljko
    Sahebkar, Amirhossein
    Sikand, Geeta
    Penson, Peter E.
    [J]. PHARMACOLOGICAL RESEARCH, 2022, 183
  • [29] The role of red yeast rice (RYR) supplementation in plasma cholesterol control: A review and expert opinion
    Banach, Maciej
    Bruckert, Eric
    Descamps, Olivier S.
    Ellegard, Lars
    Ezhov, Marat
    Foeger, Bernhard
    Fras, Zlatko
    Kovanen, Petri T.
    Latkovskis, Gustavs
    Maerz, Winfried
    Panagiotakos, Demosthenes B.
    Paragh, Gyorgy
    Pella, Daniel
    Pirillo, Angela
    Poli, Andrea
    Reiner, Zeljko
    Silbernagel, Guenter
    Viigimaa, Margus
    Vrablik, Michal
    Catapano, Alberico L.
    [J]. ATHEROSCLEROSIS SUPPLEMENTS, 2019, 39 : E1 - E8
  • [30] The Role of Nutraceuticals in Statin Intolerant Patients
    Banach, Maciej
    Patti, Angelo Maria
    Giglio, Rosaria Vincenza
    Cicero, Arrigo F. G.
    Atanasov, Atanas G.
    Bajraktari, Gani
    Bruckert, Eric
    Descamps, Olivier
    Djuric, Dragan M.
    Ezhov, Marat
    Fras, Zlatko
    von Haehling, Stephan
    Katsiki, Niki
    Langlois, Michel
    Latkovskis, Gustavs
    Mancini, G. B. John
    Mikhailidis, Dimitri P.
    Mitchenko, Olena
    Moriarty, Patrick M.
    Muntner, Paul
    Nikolic, Dragana
    Panagiotakos, Demosthenes B.
    Paragh, Gyorgy
    Paulweber, Bernhard
    Pella, Daniel
    Pitsavos, Christos
    Reiner, Zeljko
    Rosano, Giuseppe M. C.
    Rosenson, Robert S.
    Rysz, Jacek
    Sahebkar, Amirhossein
    Serban, Maria-Corina
    Vinereanu, Dragos
    Vrablik, Michal
    Watts, Gerald F.
    Wong, Nathan D.
    Rizzo, Manfredi
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2018, 72 (01) : 96 - 118
12345678910