Behavioral Modeling and its Association with PrEP and ART Use in Ugandan HIV-Serodifferent Couples

被引:0
作者
Wang, Liying [1 ]
Muwonge, Timothy R. [2 ]
Simoni, Jane M. [1 ,3 ,4 ,5 ,6 ,7 ]
Nambi, Florence [2 ]
Nakabugo, Lylianne [2 ]
Kibuuka, Joseph [2 ]
Thomas, Dorothy [3 ]
Katz, Ingrid T. [8 ,9 ]
Feutz, Erika [3 ]
Thomas, Katherine K. [3 ]
Ware, Norma C. [8 ,9 ]
Wyatt, Monique A. [8 ,10 ]
Kadama, Herbert [11 ]
Mujugira, Andrew [2 ,3 ]
Heffron, Renee [3 ,12 ]
机构
[1] Univ Washington, Dept Psychol, Seattle, WA USA
[2] Makerere Univ, Infect Dis Inst, Kampala, Uganda
[3] Univ Washington, Dept Global Hlth, Seattle, WA 98105 USA
[4] NIH, Behav & Social Sci Res, Bethesda, MD USA
[5] NIH, Off Behav & Social Sci Res OBSSR, Bethesda, MD USA
[6] NIH, Div Program Coordinat Planning & Strateg Initiat D, Bethesda, MD USA
[7] NIH, Bethesda, MD USA
[8] Harvard Med Sch, Dept Global Hlth & Social Med, 25 Shattuck St, Boston, MA USA
[9] Brigham & Womens Hosp, Dept Med, 75 Francis St, Boston, MA USA
[10] Harvard Global, Cambridge, MA USA
[11] Minist Hlth, Box 7272, Kampala, Uganda
[12] Univ Alabama Birmingham, Dept Med, 845 19th St South Bevill Biomed Res Bldg,Room 256D, Birmingham, AL 35294 USA
关键词
Observational learning; Behavioral modeling measure; HIV; Sero-different couple; Medication adherence; ANTIRETROVIRAL THERAPY; DISCORDANT COUPLES; PREVENTION; PROPHYLAXIS; ADHERENCE;
D O I
10.1007/s10461-024-04286-2
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Integrating Pre-Exposure Prophylaxis (PrEP) delivery into Antiretroviral Therapy (ART) programs bridges the Human Immunodeficiency Virus (HIV) prevention gap for HIV-serodifferent couples prior to the partner living with HIV achieving viral suppression. Behavioral modeling is one mechanism that could explain health-related behavior among couples, including those using antiretroviral medications, but few tools exist to measure the extent to which behavior is modeled. Using a longitudinal observational design nested within a cluster randomized trial, this study examined the factor structure and assessed the internal consistency of a novel 24-item, four-point Likert-type scale to measure behavioral modeling and the association of behavioral modeling with medication-taking behaviors among heterosexual, cis-gender HIV-serodifferent couples. In 149 couples enrolled for research, a five-factor model provided the best statistical and conceptual fit, including attention to partner behavior, collective action, role modeling, motivation, and relationship quality. Behavioral modeling was associated with medication-taking behaviors among members of serodifferent couples. Partner modeling of ART/PrEP taking could be an important target for assessment and intervention in HIV prevention programs for HIV serodifferent couples.
引用
收藏
页码:1719 / 1730
页数:12
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