Iron Biology - An Overview for Laboratorians

被引:0
作者
Winter, William E.
Harris, Neil S.
机构
[1] Univ Florida, Dept Pathol, Gainesville, FL USA
[2] Univ Florida, Dept Immunol & Lab Med, Gainesville, FL USA
[3] Univ Florida, Dept Pediat, Gainesville, FL USA
[4] Univ Florida, Dept Mol Genet & Microbiol, Gainesville, FL USA
关键词
TRANSFERRIN RECEPTOR; HELICOBACTER-PYLORI; SERUM FERRITIN; ANEMIA; METABOLISM; HEPCIDIN; FAMILY; COPPER; TRANSPORTER; VAGOTOMY;
D O I
暂无
中图分类号
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号
1001 ;
摘要
Iron serves a critical role in many metabolic processes, including oxygen delivery (e.g., hemoglobin) and oxygen utilization for the generation of ATP (e.g., cytochromes). Disorders of iron metabolism are best recognized and evaluated in the context of iron's absorption, transportation, monitoring, cellular uptake, and recycling. This review highlights these processes so that disorders of iron deficiency and iron excess can be better understood. Key players in iron metabolism will be highlighted, such as hepcidin, ferroportin, erythroferrone, transferrin, ferritin, HFE, and the transferrin receptors.
引用
收藏
页码:681 / 695
页数:15
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