Repression of Smad3 by silencing Robo1 attenuates epithelial-mesenchymal transition in tracheobronchial stenosis

被引：1
|
作者：
He, Chunyan [1 ]
Li, Anmao [1 ]
Gu, Lei [1 ]
Xiao, Rui [1 ]
Liao, Jiaxin [1 ]
Gan, Yiling [1 ]
Peng, Mingyu [1 ]
Guo, Shuliang [1 ]
机构：
[1] Chongqing Med Univ, Dept Pulm & Crit Care Med, Affiliated Hosp 1, Chongqing 400016, Peoples R China
来源：
CHINESE MEDICAL JOURNAL | 2023年 / 136卷 / 17期
关键词：
D O I：
10.1097/CM9.0000000000002528
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：2125 / 2127
页数：3
相关论文
共 50 条
  • [31] NANOG promotes liver cancer cell invasion by inducing epithelial-mesenchymal transition through NODAL/SMAD3 signaling pathway
    Sun, Chun
    Sun, Lu
    Jiang, Kai
    Gao, Dong-Mei
    Kang, Xiao-Nan
    Wang, Cun
    Zhang, Shu
    Huang, Shan
    Qin, Xue
    Li, Yan
    Liu, Yin-Kun
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2013, 45 (06): : 1099 - 1108
  • [32] Early growth response protein 2 promotes partial epithelial-mesenchymal transition by phosphorylating Smad3 during renal fibrosis
    Song, Anni
    Yan, Ruiwei
    Xiong, Wei
    Xiang, Huiling
    Huang, Jing
    Jiang, Anni
    Zhang, Chun
    TRANSLATIONAL RESEARCH, 2024, 271 : 13 - 25
  • [33] Elf5 Inhibits TGF-β-Driven Epithelial-Mesenchymal Transition in Prostate Cancer by Repressing SMAD3 Activation
    Yao, Bing
    Zhao, Jinsheng
    Li, Yalin
    Li, Hui
    Hu, Zhaojun
    Pan, Pan
    Zhang, Yiran
    Du, E.
    Liu, Ranlu
    Xu, Yong
    PROSTATE, 2015, 75 (08): : 872 - 882
  • [34] Effect of sufentanil on the proliferation, apoptosis, and epithelial-mesenchymal transition of ovarian cancer cells by regulating the SMAD3/SNAIL signaling pathway
    Zhao, Fei
    Liu, Guiqing
    Xiong, Lijuan
    Yao, Liang
    Wang, Lijun
    Zhang, Zheng
    JOURNAL OF MOLECULAR HISTOLOGY, 2025, 56 (02)
  • [35] GDF15 alleviates the progression of benign tracheobronchial stenosis by inhibiting epithelial-mesenchymal transition and inactivating fibroblasts
    Liao, Jiaxin
    Gan, Yiling
    Peng, Mingyu
    Giri, Mohan
    Yang, Shu
    Gu, Lei
    Li, Anmao
    Xiao, Rui
    He, Chunyan
    Li, Yishi
    Bai, Yang
    Xu, Li
    Guo, Shuliang
    EXPERIMENTAL CELL RESEARCH, 2022, 421 (02)
  • [36] Osteopontin silencing attenuates bleomycin-induced murine pulmonary fibrosis by regulating epithelial-mesenchymal transition
    Hatipoglu, Omer Faruk
    Uctepe, Eyyup
    Opoku, Gabriel
    Wake, Hidenori
    Ikemura, Kentaro
    Ohtsuki, Takashi
    Inagaki, Junko
    Gunduz, Mehmet
    Gunduz, Esra
    Watanabe, Shogo
    Nishinaka, Takashi
    Takahashi, Hideo
    Hirohata, Satoshi
    BIOMEDICINE & PHARMACOTHERAPY, 2021, 139
  • [37] Identification of Epithelial-Mesenchymal Transition-related Target Genes Induced by the Mutation of Smad3 Linker Phosphorylation (vol 23, pg 1, 2018)
    Park, Sujin
    Yang, Kyung-Min
    Park, Yuna
    Hong, Eunji
    Hong, Chang Pyo
    Park, Jinah
    Pang, Kyoungwha
    Lee, Jihee
    Park, Bora
    Lee, Siyoung
    An, Haein
    Kwak, Mi-Kyung
    Kim, Junil
    Kang, Jin Muk
    Kim, Pyunggang
    Xiao, Yang
    Nie, Guangjun
    Ooshima, Akira
    Kim, Seong-Jin
    JOURNAL OF CANCER PREVENTION, 2018, 23 (02) : 107 - 107
  • [38] EPA attenuates epithelial-mesenchymal transition and fibrosis through the TGF-β1/Smad3/ILK pathway in renal tubular epithelial HK-2 cells by up-regulating miR-541
    Wei, Zhiqiang
    Cao, Juan
    Zhang, Xu
    Yin, Di
    Xu, Deyu
    Lu, Guoyuan
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2019, 12 (07): : 2516 - 2525
  • [39] Phosphorylation status at Smad3 linker region modulates transforming growth factor-β-induced epithelial-mesenchymal transition and cancer progression
    Ooshima, Akira
    Park, Jinah
    Kim, Seong-Jin
    CANCER SCIENCE, 2019, 110 (02) : 481 - 488
  • [40] MicroRNA-92b inhibits epithelial-mesenchymal transition-induced migration and invasion by targeting Smad3 in nasopharyngeal cancer
    Zhao, Chong
    Zhao, Feipeng
    Feng, Huajun
    Xu, Shengen
    Qin, Gang
    ONCOTARGET, 2017, 8 (53) : 91603 - 91613
12345