Repression of Smad3 by silencing Robo1 attenuates epithelial-mesenchymal transition in tracheobronchial stenosis

被引：1
|
作者：
He, Chunyan [1 ]
Li, Anmao [1 ]
Gu, Lei [1 ]
Xiao, Rui [1 ]
Liao, Jiaxin [1 ]
Gan, Yiling [1 ]
Peng, Mingyu [1 ]
Guo, Shuliang [1 ]
机构：
[1] Chongqing Med Univ, Dept Pulm & Crit Care Med, Affiliated Hosp 1, Chongqing 400016, Peoples R China
来源：
CHINESE MEDICAL JOURNAL | 2023年 / 136卷 / 17期
关键词：
D O I：
10.1097/CM9.0000000000002528
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：2125 / 2127
页数：3
相关论文
共 50 条
  • [21] AZGP1 activation by lenvatinib suppresses intrahepatic cholangiocarcinoma epithelial-mesenchymal transition through the TGF-β1/Smad3 pathway
    Deng, Liming
    Bao, Wenming
    Zhang, Baofu
    Zhang, Sina
    Chen, Ziyan
    Zhu, Xuewen
    He, Bangjie
    Wu, Lijun
    Chen, Xiaohu
    Deng, Tuo
    Chen, Bo
    Yu, Zhengping
    Wang, Yi
    Chen, Gang
    CELL DEATH & DISEASE, 2023, 14 (09)
  • [22] SMAD3/Stat3 Signaling Mediates -Cell Epithelial-Mesenchymal Transition in Chronic Pancreatitis-Related Diabetes
    Xiao, Xiangwei
    Fischbach, Shane
    Zhang, Tina
    Chen, Congde
    Sheng, Qingfeng
    Zimmerman, Ray
    Patnaik, Sneha
    Fusco, Joseph
    Ming, Yungching
    Guo, Ping
    Shiota, Chiyo
    Prasadan, Krishna
    Gangopadhyay, Nupur
    Husain, Sohail Z.
    Dong, Henry
    Gittes, George K.
    DIABETES, 2017, 66 (10) : 2646 - 2658
  • [23] Response gene to complement 32 interacts with Smad3 to promote epithelial-mesenchymal transition of human renal tubular cells
    Guo, Xia
    Jose, Pedro A.
    Chen, Shi-You
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2011, 300 (06): : C1415 - C1421
  • [24] Global isonicotinylome analysis identified SMAD3 isonicotinylation promotes liver cancer cell epithelial-mesenchymal transition and invasion
    Li, Yixiao
    Jiang, Yuhan
    Yan, Haoyi
    Qin, Ziheng
    Peng, Yidi
    Lv, Danyu
    Zhang, Hongquan
    ISCIENCE, 2024, 27 (09)
  • [25] Oridonin prevents epithelial-mesenchymal transition and TGF-β1-induced epithelial-mesenchymal transition by inhibiting TGF-β1/Smad2/3 in osteosarcoma
    Sun, Yang
    Jiang, Xiubo
    Lu, Ying
    Zhu, Jianwei
    Yu, Lisha
    Ma, Bo
    Zhang, Qi
    CHEMICO-BIOLOGICAL INTERACTIONS, 2018, 296 : 57 - 64
  • [26] Natural alkaloid 8-oxo-epiberberine inhibited TGF-β1-triggred epithelial-mesenchymal transition by interfering Smad3
    Liu, Xin
    Zhang, Yiying
    Zhou, Guang-Ju
    Hou, Ying
    Kong, Qi
    Lu, Jin-Jian
    Zhang, Qingwen
    Chen, Xiuping
    TOXICOLOGY AND APPLIED PHARMACOLOGY, 2020, 404
  • [27] Sinomenine Relieves Airway Remodeling By Inhibiting Epithelial-Mesenchymal Transition Through Downregulating TGF-β1 and Smad3 Expression In Vitro and In Vivo
    He, Hongjuan
    Cao, Lihua
    Wang, Zheng
    Wang, Zhenzhen
    Miao, Jinxin
    Li, Xiu-Min
    Miao, Mingsan
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [28] Smad3 signalling plays an important role in keloid pathogenesis via epithelial-mesenchymal interactions
    Phan, TT
    Lim, IJ
    Aalami, O
    Lorget, F
    Khoo, A
    Tan, EK
    Mukhopadhyay, A
    Longaker, MT
    JOURNAL OF PATHOLOGY, 2005, 207 (02): : 232 - 242
  • [29] Smad3 signaling plays an important role in keloid pathogenesis via epithelial-mesenchymal interactions
    Phan, Thang T.
    Lim, Ivor J.
    Aalami, Oliver
    Lorget, Florence
    Khoo, Audrey
    Tan, Kim E.
    Mukhopadhaya, Anan
    Longaker, Micheal T.
    INFLAMMATION RESEARCH, 2005, 54 : S176 - S176
  • [30] Engagement of Robo1 by Slit2 induces formation of a trimeric complex consisting of Src-Robo1-E-cadherin for E-cadherin phosphorylation and epithelial-mesenchymal transition
    Tan, Qi
    Liang, Xiang-Jing
    Lin, Si-Min
    Cheng, Yuanxiong
    Ding, Yan-Qing
    Liu, Teng-Fei
    Zhou, Wei-Jie
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2020, 522 (03) : 757 - 762
12345