Synthesis, Crystal Structure, and Activity of Cu(II) and Zn(II) Complexes of 2-Mercaptoquinoline N-Oxide

被引:0
|
作者
Ji, J. [1 ]
Li, H. [2 ]
Liu, C. [1 ]
Chen, Y. [1 ]
Li, R. [3 ]
Zhang, Z. [1 ]
机构
[1] Jiangsu Ocean Univ, Sch Environm & Chem Engn, Lianyungang 222005, Peoples R China
[2] Jiangsu Ocean Univ, Sch Pharm, Lianyungang 222005, Peoples R China
[3] Sichuan Univ, Sch Polymer Sci & Engn, Chengdu 610065, Peoples R China
基金
中国国家自然科学基金;
关键词
2-mercaptoquinoline N-oxide; Cu(II) complexes; Zn(II) complexes; antibacterial activity; ZINC PYRITHIONE; MECHANISM;
D O I
10.1134/S1070363223010243
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The mononuclear Cu(II) complex, Zn(II) complex, and homodinuclear Zn(II)-Zn(II) complex of 2-mercaptoquinoline N-oxide, have been synthesized as possible antibacterial agents. Their crystal structures analyzed by X-ray diffraction methods have shown that the structures of the two mononuclear complexes and a homodinuclear complex are markedly different. The antibacterial activities of complexes were investigated using the Oxford Cup method, and the result indicated that complexes have good antibacterial activity against Escherichia coli, Staphylococcus aureus, and Candida albicans.
引用
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页码:182 / 188
页数:7
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