Magnetic Micro/nanorobots for biological detection and targeted delivery

被引:11
作者
Deng, Xue [1 ]
Su, Yuan [2 ]
Xu, Minghao [1 ]
Gong, De [4 ]
Cai, Jun [4 ]
Akhter, Muhammad [5 ]
Chen, Kehan [1 ]
Li, Shuting [2 ]
Pan, Jingwen [1 ]
Gao, Chao [1 ]
Li, Daoliang
Zhang, Wenqiang [1 ,6 ]
Xu, Wentao [2 ,3 ,7 ]
机构
[1] China Agr Univ, Coll Engn, Beijing 100083, Peoples R China
[2] China Agr Univ, Inst Nutr & Hlth, Dept Nutr & Hlth, Key Lab Precis Nutr & Food Qual, Beijing 100083, Peoples R China
[3] China Agr Univ, Coll Food Sci & Nutr Engn, Key Lab Safety Assessment Genet Modified Organism, Beijing 100083, Peoples R China
[4] Beihang Univ, Sch Mech Engn & Automat, Beijing 100191, Peoples R China
[5] China Agr Univ, Coll Informat & Elect Engn, Beijing 100083, Peoples R China
[6] China Agr Univ, Coll Engn, Tsinghua East Rd 17, Beijing, Peoples R China
[7] China Agr Univ, Dept Nutr & Hlth, Lab precis Nutr & Food Qual, Tianxiu Rd 10, Beijing, Peoples R China
基金
中国国家自然科学基金;
关键词
Magnetic micro; nanorobot; Functionalization; Detection; Targeted delivery; DRUG-DELIVERY; MAGNETOTACTIC BACTERIA; CATALYTIC NANOMOTORS; CARGO DELIVERY; NANOPARTICLES; MICROMOTORS; DRIVEN; NANOLIPOSOMES; MICROROBOT; ENDOTOXIN;
D O I
10.1016/j.bios.2022.114960
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Micro/nanorobots can effectively convert a variety of energy sources into power, thereby providing highly effective resources for human beings at the micro/nanoscale. Magnetic micro/nanorobots have attracted significant attention, particularly in the fields of biological detection and targeted delivery, based on their unique motion charac-teristics, non-damaging penetration through biological tissues, and wireless remote control manipulability. In recent years, progress in the design, manufacturing, and operation of magnetic micro/nanorobots has significantly promoted their functional integrity and applicability, and demonstrated their significant potential for biomedicine. This re-view summarises the latest applications and future development pros-pects of magnetic micro/nanorobots in the fields of biological detection and targeted delivery. The concepts of connotation, driving modes, and functional strategies of magnetic micro/nanorobots are also introduced. Finally, the potential advantages and future research directions of magnetic micro/nanorobots are discussed, providing clear evidence that the progressive integration of robots, detection, medicine, and other technologies will have a significant impact on future biomedical applications.
引用
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页数:15
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