共 166 条
Nanocellulose-based sensors in medical/clinical applications: The state-of-the-art review
被引:31
作者:

论文数: 引用数:
h-index:
机构:

论文数: 引用数:
h-index:
机构:

论文数: 引用数:
h-index:
机构:
机构:
[1] Univ Basque Country UPV EHU, Fac Engn, Chem & Environm Engn Dept, Biorefinery Proc Res Grp, Plaza Europa 1, Donostia San Sebastian 20018, Spain
[2] Babol Noshirvani Univ Technol, Chem Engn Dept, Shariati St, Babol 4714871167, Iran
关键词:
Nanocellulose;
Biosensor;
Chemical sensor;
Physical sensor;
Healthcare monitoring;
CELLULOSE NANOCRYSTALS;
SURFACE MODIFICATION;
NANOMATERIALS;
NANOCOMPOSITE;
BIOSENSORS;
OXIDE;
DISCRIMINATION;
NANOPARTICLES;
POLYANILINE;
ELECTRODES;
D O I:
10.1016/j.carbpol.2022.120509
中图分类号:
O69 [应用化学];
学科分类号:
081704 ;
摘要:
In recent years, the considerable importance of healthcare and the indispensable appeal of curative issues, particularly the diagnosis of diseases, have propelled the invention of sensing platforms. With the development of nanotechnology, the integration of nanomaterials in such platforms has been much focused on, boosting their functionality in many fields. In this direction, there has been rapid growth in the utilisation of nanocellulose in sensors with medical applications. Indeed, this natural nanomaterial benefits from striking features, such as biocompatibility, cytocompatibility and low toxicity, as well as unprecedented physical and chemical properties. In this review, different classifications of nanocellulose-based sensors (biosensors, chemical and physical sen-sors), alongside some subcategories manufactured for health monitoring, stand out. Moreover, the types of nanocellulose and their roles in such sensors are discussed.
引用
收藏
页数:20
相关论文
共 166 条
[61]
Biotech nanocellulose: A review on progress in product design and today's state of technical and medical applications
[J].
Klemm, Dieter
;
Petzold-Welcke, Katrin
;
Kramer, Friederike
;
Richter, Thomas
;
Raddatz, Vanessa
;
Fried, Wolfgang
;
Nietzsche, Sandor
;
Bellmann, Tom
;
Fischer, Dagmar
.
CARBOHYDRATE POLYMERS,
2021, 254

Klemm, Dieter
论文数: 0 引用数: 0
h-index: 0
机构:
KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany

Petzold-Welcke, Katrin
论文数: 0 引用数: 0
h-index: 0
机构:
KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany

Kramer, Friederike
论文数: 0 引用数: 0
h-index: 0
机构:
KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany
Univ Hosp Jena, Dept Orthoped, Expt Rheumatol Unit, Waldkliniken Eisenberg, Klosterlausnitzerstr 81, D-07607 Eisenberg, Germany KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany

Richter, Thomas
论文数: 0 引用数: 0
h-index: 0
机构:
Polymet Jena Assoc, Hans Knoll Str 6, D-07745 Jena, Germany
SurA Chem, Posener Weg 2, D-07751 Bucha, Germany KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany

Raddatz, Vanessa
论文数: 0 引用数: 0
h-index: 0
机构:
KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany

Fried, Wolfgang
论文数: 0 引用数: 0
h-index: 0
机构:
KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany

Nietzsche, Sandor
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Hosp Jena, Ctr Electron Microscopy, Ziegelmuehlenweg 1, D-07743 Jena, Germany KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany

Bellmann, Tom
论文数: 0 引用数: 0
h-index: 0
机构:
Friedrich Schiller Univ Jena, Dept Pharmaceut Technol & Biopharm, Lessingstr 8, D-07743 Jena, Germany KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany

Fischer, Dagmar
论文数: 0 引用数: 0
h-index: 0
机构:
Friedrich Schiller Univ Jena, Dept Pharmaceut Technol & Biopharm, Lessingstr 8, D-07743 Jena, Germany KKF Gesell, Hans Knoll Str 6, D-07745 Jena, Germany
[62]
Cellulose-Based Nanofibers Processing Techniques and Methods Based on Bottom-Up Approach-A Review
[J].
Kramar, Ana
;
Gonzalez-Benito, Francisco Javier
.
POLYMERS,
2022, 14 (02)

Kramar, Ana
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Carlos III Madrid, Inst Tecnol Quim & Mat Alvaro Alonso Barba, Dept Mat Sci & Engn & Chem Engn, Avda Univ 30, Leganes 28911, Spain Univ Carlos III Madrid, Inst Tecnol Quim & Mat Alvaro Alonso Barba, Dept Mat Sci & Engn & Chem Engn, Avda Univ 30, Leganes 28911, Spain

Gonzalez-Benito, Francisco Javier
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Carlos III Madrid, Inst Tecnol Quim & Mat Alvaro Alonso Barba, Dept Mat Sci & Engn & Chem Engn, Avda Univ 30, Leganes 28911, Spain Univ Carlos III Madrid, Inst Tecnol Quim & Mat Alvaro Alonso Barba, Dept Mat Sci & Engn & Chem Engn, Avda Univ 30, Leganes 28911, Spain
[63]
A comprehensive review on production, surface modification and characterization of nanocellulose derived from biomass and its commercial applications
[J].
Kumar, R.
;
Rai, B.
;
Gahlyan, S.
;
Kumar, G.
.
EXPRESS POLYMER LETTERS,
2021, 15 (02)
:104-120

论文数: 引用数:
h-index:
机构:

Rai, B.
论文数: 0 引用数: 0
h-index: 0
机构:
Shriram Inst Ind Res, Mat Sci Div, 19 Univ Rd, Delhi 110007, India Guru Gobind Singh Indraprastha Univ, Univ Sch Basic & Appl Sci, New Delhi 110078, India

Gahlyan, S.
论文数: 0 引用数: 0
h-index: 0
机构:
Deenbandhu Chhotu Ram Univ Sci & Technol, Dept Chem, Murthal 131039, India Guru Gobind Singh Indraprastha Univ, Univ Sch Basic & Appl Sci, New Delhi 110078, India

论文数: 引用数:
h-index:
机构:
[64]
Two-Photon Dual-Emissive Carbon Dot-Based Probe: Deep-Tissue Imaging and Ultrasensitive Sensing of Intracellular Ferric Ions
[J].
Lesani, Pooria
;
Singh, Gurvinder
;
Viray, Christina
;
Ramaswamy, Yogambha
;
Zhu, De Ming
;
Kingshott, Peter
;
Lu, Zufu
;
Zreiqat, Hala
.
ACS APPLIED MATERIALS & INTERFACES,
2020, 12 (16)
:18395-18406

Lesani, Pooria
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia
Univ Sydney, ARC Training Ctr Innovat BioEngn, Sydney, NSW 2006, Australia Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia

Singh, Gurvinder
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia
Univ Sydney, ARC Training Ctr Innovat BioEngn, Sydney, NSW 2006, Australia Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia

Viray, Christina
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia
Univ Sydney, ARC Training Ctr Innovat BioEngn, Sydney, NSW 2006, Australia Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia

Ramaswamy, Yogambha
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia
Univ Sydney, ARC Training Ctr Innovat BioEngn, Sydney, NSW 2006, Australia Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia

Zhu, De Ming
论文数: 0 引用数: 0
h-index: 0
机构:
Swinburne Univ Technol, Sch Sci, Dept Chem & Biotechnol, Hawthorn, Vic 3122, Australia Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia

论文数: 引用数:
h-index:
机构:

Lu, Zufu
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia
Univ Sydney, ARC Training Ctr Innovat BioEngn, Sydney, NSW 2006, Australia Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia

Zreiqat, Hala
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia
Univ Sydney, ARC Training Ctr Innovat BioEngn, Sydney, NSW 2006, Australia Univ Sydney, Tissue Engn & Biomat Res Unit, Sch Biomed Engn, Sydney, NSW 2006, Australia
[65]
A novel near -infrared turn -on fluorescent probe for the detection of Fe 3+and Al 3+and its applications in living cells imaging
[J].
Li, Bai
;
Mei, Huihui
;
Chang, Yongxin
;
Xu, Kuoxi
;
Yang, Li
.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY,
2020, 239

Li, Bai
论文数: 0 引用数: 0
h-index: 0
机构:
Henan Univ, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China Henan Univ, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China

Mei, Huihui
论文数: 0 引用数: 0
h-index: 0
机构:
Henan Univ, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China Henan Univ, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China

Chang, Yongxin
论文数: 0 引用数: 0
h-index: 0
机构:
Henan Univ, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China Henan Univ, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China

Xu, Kuoxi
论文数: 0 引用数: 0
h-index: 0
机构:
Henan Univ, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China Henan Univ, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China

Yang, Li
论文数: 0 引用数: 0
h-index: 0
机构:
Henan Univ, Inst Pharm, Kaifeng 475004, Henan, Peoples R China Henan Univ, Coll Chem & Chem Engn, Kaifeng 475004, Peoples R China
[66]
Biosensor based on bacterial cellulose-Au nanoparticles electrode modified with laccase for hydroquinone detection
[J].
Li, Guohui
;
Sun, Kaiyue
;
Li, Dawei
;
Lv, Pengfei
;
Wang, Qingqing
;
Huang, Fenglin
;
Wei, Qufu
.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,
2016, 509
:408-414

Li, Guohui
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Sun, Kaiyue
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Li, Dawei
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Lv, Pengfei
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Wang, Qingqing
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Huang, Fenglin
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Wei, Qufu
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Minist Educ, Key Lab Ecotext, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China
[67]
Encapsulating enzyme into metal-organic framework during in-situ growth on cellulose acetate nanofibers as self-powered glucose biosensor
[J].
Li, Xin
;
Feng, Quan
;
Lu, Keyu
;
Huang, Jieyu
;
Zhang, Yanan
;
Hou, Yutong
;
Qiao, Hui
;
Li, Dawei
;
Wei, Qufu
.
BIOSENSORS & BIOELECTRONICS,
2021, 171 (171)

Li, Xin
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Feng, Quan
论文数: 0 引用数: 0
h-index: 0
机构:
Anhui Polytech Univ, Key Lab Text Fabr, Wuhu 241000, Anhui, Peoples R China Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Lu, Keyu
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, State Key Lab Food Sci & Technol, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Huang, Jieyu
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Zhang, Yanan
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Hou, Yutong
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Qiao, Hui
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Li, Dawei
论文数: 0 引用数: 0
h-index: 0
机构:
Nantong Univ, Coll Text & Clothing, Nantong 226019, Jiangsu, Peoples R China Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China

Wei, Qufu
论文数: 0 引用数: 0
h-index: 0
机构:
Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China Jiangnan Univ, Key Lab Ecotext, Minist Educ, 1800 Lihu Ave, Wuxi 214122, Jiangsu, Peoples R China
[68]
Flex-GO (Flexible graphene oxide) sensor for electrochemical monitoring lactate in low-volume passive perspired human sweat
[J].
Lin, Kai-Chun
;
Muthukumar, Sriram
;
Prasad, Shalini
.
TALANTA,
2020, 214

Lin, Kai-Chun
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Texas Dallas, Dept Bioengn, 800 West Campbell Rd, Richardson, TX 75080 USA Univ Texas Dallas, Dept Bioengn, 800 West Campbell Rd, Richardson, TX 75080 USA

Muthukumar, Sriram
论文数: 0 引用数: 0
h-index: 0
机构:
Enlisense LLC, 1813 Audubon Pond Way, Allen, TX 75013 USA Univ Texas Dallas, Dept Bioengn, 800 West Campbell Rd, Richardson, TX 75080 USA

Prasad, Shalini
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Texas Dallas, Dept Bioengn, 800 West Campbell Rd, Richardson, TX 75080 USA Univ Texas Dallas, Dept Bioengn, 800 West Campbell Rd, Richardson, TX 75080 USA
[69]
Synthesis and characterisation of nanocellulose-based polyaniline conducting films
[J].
Liu, D. Y.
;
Sui, G. X.
;
Bhattacharyya, D.
.
COMPOSITES SCIENCE AND TECHNOLOGY,
2014, 99
:31-36

Liu, D. Y.
论文数: 0 引用数: 0
h-index: 0
机构:
Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China

Sui, G. X.
论文数: 0 引用数: 0
h-index: 0
机构:
Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China Chinese Acad Sci, Inst Met Res, Shenyang 110016, Peoples R China

论文数: 引用数:
h-index:
机构:
[70]
Laser-induced graphene (LIG)-driven medical sensors for health monitoring and diseases diagnosis
[J].
Liu, Jianlei
;
Ji, Haijie
;
Lv, Xiaoyan
;
Zeng, Chijia
;
Li, Heming
;
Li, Fugang
;
Qu, Bin
;
Cui, Feiyun
;
Zhou, Qin
.
MICROCHIMICA ACTA,
2022, 189 (02)

Liu, Jianlei
论文数: 0 引用数: 0
h-index: 0
机构:
Foshan Fosun Chancheng Hosp, Dept Lab Med & Pathol, Foshan 528000, Guangdong, Peoples R China Foshan Fosun Chancheng Hosp, Dept Lab Med & Pathol, Foshan 528000, Guangdong, Peoples R China

Ji, Haijie
论文数: 0 引用数: 0
h-index: 0
机构:
Chongqing Med Univ, Sch Lab Med, Key Lab Clin Diagnost, Minist Educ, Chongqing 400016, Peoples R China Foshan Fosun Chancheng Hosp, Dept Lab Med & Pathol, Foshan 528000, Guangdong, Peoples R China

Lv, Xiaoyan
论文数: 0 引用数: 0
h-index: 0
机构:
Sichuan Univ, West China Hosp, West China Sch Med, Dept Dermatol, Chengdu 610041, Peoples R China Foshan Fosun Chancheng Hosp, Dept Lab Med & Pathol, Foshan 528000, Guangdong, Peoples R China

Zeng, Chijia
论文数: 0 引用数: 0
h-index: 0
机构:
Foshan Fosun Chancheng Hosp, Dept Lab Med & Pathol, Foshan 528000, Guangdong, Peoples R China Foshan Fosun Chancheng Hosp, Dept Lab Med & Pathol, Foshan 528000, Guangdong, Peoples R China

Li, Heming
论文数: 0 引用数: 0
h-index: 0
机构:
Harbin Med Univ, Coll Basic Med Sci, Harbin 150081, Peoples R China Foshan Fosun Chancheng Hosp, Dept Lab Med & Pathol, Foshan 528000, Guangdong, Peoples R China

Li, Fugang
论文数: 0 引用数: 0
h-index: 0
机构:
Shanghai Upper Bio Tech Pharma Co Ltd, Shanghai Ind Technol Innovat Strateg Alliance iPO, Shanghai Engn Res Ctr iPOCT Med, Shanghai 201201, Peoples R China Foshan Fosun Chancheng Hosp, Dept Lab Med & Pathol, Foshan 528000, Guangdong, Peoples R China

Qu, Bin
论文数: 0 引用数: 0
h-index: 0
机构:
Univ Saarland, Sch Med, Ctr Integrat Physiol & Mol Med CIPMM, Biophys, D-66421 Homburg, Germany Foshan Fosun Chancheng Hosp, Dept Lab Med & Pathol, Foshan 528000, Guangdong, Peoples R China

Cui, Feiyun
论文数: 0 引用数: 0
h-index: 0
机构:
Chongqing Med Univ, Sch Lab Med, Key Lab Clin Diagnost, Minist Educ, Chongqing 400016, Peoples R China Foshan Fosun Chancheng Hosp, Dept Lab Med & Pathol, Foshan 528000, Guangdong, Peoples R China

Zhou, Qin
论文数: 0 引用数: 0
h-index: 0
机构:
Harbin Med Univ, Coll Basic Med Sci, Harbin 150081, Peoples R China Foshan Fosun Chancheng Hosp, Dept Lab Med & Pathol, Foshan 528000, Guangdong, Peoples R China