Chronic and Neurotropic: A Paradigm-Challenging Case of Dengue Virus Encephalitis in a Patient With Advanced Human Immunodeficiency Virus Infection

被引:3
作者
Marinelli, Tina [1 ,8 ]
Masters, Jeffrey [1 ,2 ]
Buckland, Michael E. [3 ,4 ]
Lee, Maggie [3 ]
Rawlinson, William [5 ,6 ]
Kim, Ki Wook [6 ]
Urriola, Nicolas [7 ]
van Hal, Sebastiaan [1 ,8 ]
机构
[1] Royal Prince Alfred Hosp, Dept Infect Dis & Microbiol, Sydney, NSW, Australia
[2] Univ New South Wales, Kirby Inst, Sydney, NSW, Australia
[3] Royal Prince Alfred Hosp, Dept Neuropathol, Sydney, NSW, Australia
[4] Univ Sydney, Sch Med Sci, Sydney, NSW, Australia
[5] New South Wales Hlth Pathol, Dept Microbiol, Serol & Virol Div, Sydney, NSW, Australia
[6] Univ New South Wales, Fac Med & Hlth, Sch Clin Med, Sydney, NSW, Australia
[7] Royal Prince Alfred Hosp, Dept Clin Immunol & Allergy, Sydney, NSW, Australia
[8] Royal Prince Alfred Hosp, Dept Infect Dis & Microbiol, 50 Missenden Rd, Sydney, NSW 2050, Australia
关键词
encephalitis; dengue virus; human immunodeficiency virus; metagenomic sequencing; case report;
D O I
10.1093/cid/ciae061
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A 32-year-old female with advanced human immunodeficiency virus infection presented to an Australian hospital with subacute, worsening symptoms of encephalitis. Metagenomic sequencing and Dengue NS3 antigen staining of brain tissue confirmed active dengue virus (DENV) encephalitis. The most recent possible DENV exposure was months prior in West Africa, indicating chronicity.
引用
收藏
页码:498 / 501
页数:4
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