Genetic and process engineering for polyhydroxyalkanoate production from pre- and post-consumer food waste

被引：14

作者：

Chacon, Micaela ^{[1
]}

Wongsirichot, Phavit ^{[2
]}

Winterburn, James ^{[2
]}

Dixon, Neil ^{[1
]}

机构：

[1] Univ Manchester, Manchester Inst Biotechnol MIB, Dept Chem, Manchester M1 7DN, England

[2] Univ Manchester, Dept Chem Engn, Oxford Rd, Manchester M13 9PL, Lancashire, England

来源：

CURRENT OPINION IN BIOTECHNOLOGY | 2024年 / 85卷

基金：

英国生物技术与生命科学研究理事会;

关键词：

FED-BATCH CULTURE; PSEUDOMONAS-PUTIDA; RALSTONIA-EUTROPHA; HALOMONAS-BLUEPHAGENESIS; UTILIZATION ABILITY; GROWTH; GLYCEROL; GLUCOSE; XYLOSE; PHB;

D O I：

10.1016/j.copbio.2023.103024

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Biopolymers produced as microbial carbon storage systems, such as polyhydroxyalkanoates (PHAs), offer potential to be used in place of petrochemically derived plastics. Low-value organic feedstocks, such as food waste, have been explored as a potential substrate for the microbial production of PHAs. In this review, we discuss the biosynthesis, composition and producers of PHAs, with a particular focus on the genetic and process engineering efforts to utilise non-native substrates, derived from food waste from across the entire supply chain, for microbial growth and PHA production. We highlight a series of studies that have achieved impressive advances and discuss the challenges of producing PHAs with consistent composition and properties from mixed and variable food waste and byproducts.

引用

页数：11

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