Advances in the Construction and Application of Thyroid Organoids

被引：1
作者：
Zhang, Yuhan [1 ,2 ]
Fu, Mengfei [1 ,2 ]
Wang, Hanyu [1 ,2 ]
Sun, Hui [1 ,2 ]
机构：
[1] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Dept Endocrinol, Wuhan, Peoples R China
[2] Hubei Prov Clin Res Ctr Diabet & Metab Disorders, Wuhan, Peoples R China
来源：
PHYSIOLOGICAL RESEARCH | 2023年 / 72卷 / 05期
关键词：
Organoids; Stem cells; Thyroid; Thyroid cancer; EMBRYONIC STEM-CELLS; PROGENITORS; GENERATION;
D O I：
10.33549/physiolres.935102
中图分类号：
Q4 [生理学];
学科分类号：
071003 ;
摘要：
Organoids are complex multicellular structures that stem cells self-organize in three-dimensional (3D) cultures into anatomical structures and functional units similar to those seen in the organs from which they originate. This review describes the construction of thyroid organoids and the research progress that has occurred in models of thyroid-related disease. As a novel tool for modeling in a 3D multicellular environment, organoids help provide some useful references for the study of the pathogenesis of thyroid disease.
引用
收藏
页码：557 / 564
页数：8
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