Ultrasound contrast-enhanced diagnosis of testicular Leydig cell tumor: A case report and literature review

Leydig cell tumor (LCT) is a rare testicular tumor. We report a case of an elderly male patient who discovered a left testicular mass during a regular health examination four years ago. The patient did not experience any significant discomfort and opted for regular follow-up visits. During the most recent visit, we performed routine ultrasound and contrast-enhanced ultrasound (CEUS) examinations. By observing the lesion's location, echogenicity, margins, vascular distribution, as well as the rapid enhancement and slow washout characteristics on contrast-enhanced ultrasound, we arrived at a diagnosis of LCT. Subsequently, the patient underwent left inguinal orchiectomy. Postoperative pathology and immunohistochemistry confirmed the diagnosis of LCT. Additionally, we conducted a comprehensive review of LCT-related literature from PubMed and SCOPUS, summarizing the clinical features, follow-up duration, prognosis, and ultrasound characteristics associated with LCT. This article describes a rare case of testicular Leydig cell tumor and provides an analysis of the case using roution ultrasound, color Doppler ultrasound, and contrast-enhanced ultrasound. Relevant literature from recent years was also reviewed to summarize the typical ultrasound features, clinical characteristics, and prognosis of testicular Leydig cell tumors. image