Jejunal Angiodysplasia in an Elderly Patient with Aortic Stenosis: Significance of Von Willebrand Factor as an Etiologic Factor

被引：2

作者：

Kubo, Toshiyuki ^{[1
,2
]}

Yoshii, Shinji ^{[1
]}

Yamano, Hiro-o ^{[1
]}

Saito, Masato ^{[3
]}

Sakata, Koichi ^{[3
]}

Sugita, Shintaro ^{[4
]}

Hasegawa, Tadashi ^{[4
]}

Horiuchi, Hisanori ^{[5
]}

Nakase, Hiroshi ^{[1
]}

机构：

[1] Sapporo Med Univ, Dept Gastroenterol & Hepatol, Sch Med, Sapporo, Japan

[2] Sapporo Shirakaba dai Hosp, Dept Gastroenterol & Hepatol, Sapporo, Japan

[3] Sapporo Med Univ, Sch Med, Dept Radiol Oncol, Sapporo, Japan

[4] Sapporo Med Univ, Sch Med, Dept Surg Pathol, Sapporo, Japan

[5] Tohoku Univ, Inst Dev Aging & Canc, Dept Mol & Cellular Biol, Sendai, Japan

来源：

INTERNAL MEDICINE | 2023年 / 62卷 / 14期

关键词：

Heyde's syndrome; aortic stenosis; von Willebrand factor; angiodysplasia; vascular disease; GASTROINTESTINAL ANGIODYSPLASIA; HEYDES SYNDROME;

D O I：

10.2169/internalmedicine.0888-22

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heyde's syndrome is a disease in which patients with aortic stenosis (AS) bleed from angiodysplasia. An 80-year-old woman with a history of severe AS was referred to our hospital with melena and anemia. The patient underwent jejunal resection after repeated blood transfusions. A pathological examination revealed angiodysplasia, and the patient's plasma lacked high-molecular-weight von Willebrand factor (VWF) multimers, leading to the diagnosis of Heyde's syndrome. The patient underwent transcatheter aortic valve implantation (TAVI) one year after the diagnosis, and the VWF index recovered. This is a valuable case in which the pathological analysis of angiodysplasia associated with Heyde's syndrome was possible.

引用

页码：2059 / 2062

页数：4

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