Recent Advances in Potential Health Benefits of Quercetin

被引:160
|
作者
Aghababaei, Fatemeh [1 ]
Hadidi, Milad [2 ]
机构
[1] Univ Autonoma Barcelona, Ctr Innovacio Recerca & Transferencia Tecnol Alime, Dept Ciencia Anim & Aliments, TECNIO UAB,XIA, UAB Campus, Bellaterra 08193, Spain
[2] Univ Castilla La Mancha, Fac Chem Sci & Technol, Dept Organ Chem, Ciudad Real 13071, Spain
关键词
antioxidative activity; free radicals; anticancer activity; anti-inflammatory; chronic diseases; pharmaceutical applications; 1000 SUCCINATE NANOPARTICLES; IN-VITRO; PROSTATE-CANCER; FLAVONOID QUERCETIN; DIETARY FLAVONOIDS; INDUCED APOPTOSIS; INDUCED NEPHROTOXICITY; BLOOD-PRESSURE; ORAL DELIVERY; CO-DELIVERY;
D O I
10.3390/ph16071020
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Quercetin, a flavonoid found in fruits and vegetables, has been a part of human diets for centuries. Its numerous health benefits, including antioxidant, antimicrobial, anti-inflammatory, antiviral, and anticancer properties, have been extensively studied. Its strong antioxidant properties enable it to scavenge free radicals, reduce oxidative stress, and protect against cellular damage. Quercetin's anti-inflammatory properties involve inhibiting the production of inflammatory cytokines and enzymes, making it a potential therapeutic agent for various inflammatory conditions. It also exhibits anticancer effects by inhibiting cancer cell proliferation and inducing apoptosis. Finally, quercetin has cardiovascular benefits such as lowering blood pressure, reducing cholesterol levels, and improving endothelial function, making it a promising candidate for preventing and treating cardiovascular diseases. This review provides an overview of the chemical structure, biological activities, and bioavailability of quercetin, as well as the different delivery systems available for quercetin. Incorporating quercetin-rich foods into the diet or taking quercetin supplements may be beneficial for maintaining good health and preventing chronic diseases. As research progresses, the future perspectives of quercetin appear promising, with potential applications in nutraceuticals, pharmaceuticals, and functional foods to promote overall well-being and disease prevention. However, further studies are needed to elucidate its mechanisms of action, optimize its bioavailability, and assess its long-term safety for widespread utilization.
引用
收藏
页数:31
相关论文
共 50 条
  • [21] Molecular mechanisms of action of quercetin in cancer: recent advances
    Kashyap, Dharambir
    Mittal, Sonam
    Sak, Katrin
    Singhal, Paavan
    Tuli, Hardeep Singh
    TUMOR BIOLOGY, 2016, 37 (10) : 12927 - 12939
  • [22] The Potential Benefits of Applying Recent Advances in esophageal Motility Testing in Patients with esophageal Atresia
    Rommel, Nathalie
    Rayyan, Maissa
    Scheerens, Charlotte
    Omari, Taher
    FRONTIERS IN PEDIATRICS, 2017, 5
  • [23] Recent Developments in Fermented Cereals on Nutritional Constituents and Potential Health Benefits
    Zhang, Jiayan
    Liu, Mengting
    Zhao, Yansheng
    Zhu, Ying
    Bai, Juan
    Fan, Songtao
    Zhu, Lin
    Song, Ci
    Xiao, Xiang
    FOODS, 2022, 11 (15)
  • [24] Kombucha Healthy Drink-Recent Advances in Production, Chemical Composition and Health Benefits
    Kitwetcharoen, Haruthairat
    Phung, Ly Tu
    Klanrit, Preekamol
    Thanonkeo, Sudarat
    Tippayawat, Patcharaporn
    Yamada, Mamoru
    Thanonkeo, Pornthap
    FERMENTATION-BASEL, 2023, 9 (01):
  • [25] Recent Advances in the Understanding of the Health Benefits and Molecular Mechanisms Associated with Green Tea Polyphenols
    Xing, Lujuan
    Zhang, Hua
    Qi, Ruili
    Tsao, Rong
    Mine, Yoshinori
    JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2019, 67 (04) : 1029 - 1043
  • [26] Recent Advances in the Health Benefits and Application of Tangerine Peel (Citri Reticulatae Pericarpium): A Review
    Shi, Minke
    Guo, Qihan
    Xiao, Zhewen
    Sarengaowa, Ying
    Xiao, Ying
    Feng, Ke
    FOODS, 2024, 13 (13)
  • [27] Recent advances on camel milk: Nutritional and health benefits and processing implications-A review
    Seifu, Eyassu
    AIMS AGRICULTURE AND FOOD, 2022, 7 (04): : 777 - 804
  • [28] Recent Advances in the Distribution, Chemical Composition, Health Benefits, and Application of the Fruit of Siraitia grosvenorii
    Guo, Qihan
    Shi, Minke
    Sarengaowa, Zhewen
    Xiao, Zhewen
    Xiao, Ying
    Feng, Ke
    FOODS, 2024, 13 (14)
  • [29] Recent advances in benefits and hazards of engineered nanoparticles
    Radad, Khaled
    Al-Shraim, Mubarak
    Moldzio, Rudolf
    Rausch, Wolf-Dieter
    ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 2012, 34 (03) : 661 - 672
  • [30] Recent advances on bioactive compounds, health benefits, and potential applications of jujube (Ziziphus Jujuba Mill.): A perspective of by-products valorization
    Zhu, Jinpeng
    Lu, Yunhao
    He, Qiang
    TRENDS IN FOOD SCIENCE & TECHNOLOGY, 2024, 145