Hypertension in non-obese children and BMI in adulthood: the Bogalusa heart study

被引:1
|
作者
Zhao, Lingli [1 ,2 ]
Qu, Hua [1 ,2 ]
Ouyang, Jiahui [3 ]
Meng, Yanyan [1 ,2 ]
Gao, Zhuye [1 ,2 ]
机构
[1] China Acad Chinese Med Sci, Xiyuan Hosp, Dept Nephropathy, 1 Xiyuan Playground, Beijing 100091, Peoples R China
[2] Natl Clin Res Ctr Chinese Med Cardiol, Beijing 100091, Peoples R China
[3] Beijing Univ Chinese Med, Beijing 100029, Peoples R China
关键词
Hypertension; Body mass index; Regression analysis; Low-density lipoprotein cholesterol; Risk factors; Database; Gut microbiota; Inflammation; OXIDATIVE STRESS; BLOOD-PRESSURE; CARDIOVASCULAR-DISEASE; OBESITY; RISK;
D O I
10.1186/s12872-023-03699-6
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
ObjectiveThis study explored the association between hypertension(HTN) in non-obese children body mass index (BMI) in adulthood.MethodsA retrospective analysis of 1111 participants from the Bogalusa Heart Study was conducted, in which data on hypertension history during childhood in non-obese children, anthropometric and cardiovascular risk factors and other indicators from cross-sectional examinations in adulthood were collected. BMI was used as both a continuous and a categorical variable, and multivariate linear regression modelling and logistic regression modelling were used.ResultsOf the 1111 participants finally enrolled, 40 (3.60%) had HTN during childhood. After adjusting for demographic characteristics, lipid, glucose and insulin levels in childhood, and smoking status, alcohol intake, and disease history as adults, HTN among non-obese children was positively associated with BMI in adulthood (beta = 2.64 kg/m2, 95% CI: 0.88-4.40, P = 0.0033), and the odds of being overweight or obese was 3.71 times higher in the group with a history of hypertension in childhood than those without a history of HTN(95% CI: 1.11-12.46, P = 0.0337).ConclusionAmong non-obese children, hypertension is at risk for higher levels of BMI in adulthood. Identifying and controlling blood pressure and childhood may aid in the prevention of adult obesity.
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页数:7
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