Biomechanical evaluation of CAD/CAM magnesium miniplates as a fixation strategy for the treatment of segmental mandibular reconstruction with a fibula free flap

被引：5

作者：

Ruf, Philipp ^{[1
,2
,3
,4
,5
,6
]}

Orassi, Vincenzo ^{[1
,6
]}

Fischer, Heilwig ^{[2
,3
,4
,5
,6
]}

Steffen, Claudius ^{[2
,3
,4
,5
,6
]}

Kreutzer, Kilian ^{[2
,3
,4
,5
,6
]}

Duda, Georg N. ^{[1
,6
]}

Heiland, Max ^{[2
,3
,4
,5
,6
]}

Checa, Sara ^{[1
,6
]}

Rendenbach, Carsten ^{[2
,3
,4
,5
]}

机构：

[1] Charite Univ Med Berlin, Berlin Inst Hlth, Julius Wolff Inst, Augustenburger Pl 1, D-13353 Berlin, Germany

[2] Charite, Dept Oral & Maxillofacial Surg, Augustenburger Pl 1, D-13353 Berlin, Germany

[3] Humboldt Univ, Augustenburger Pl 1, D-13353 Berlin, Germany

[4] Free Univ Berlin, Augustenburger Pl 1, D-13353 Berlin, Germany

[5] Berlin Inst Hlth, Augustenburger Pl 1, D-13353 Berlin, Germany

[6] Charite Univ Med Berlin, BIH Biomed Innovat Acad, BIH Charite Clinician Scientist Program, Berlin Inst Hlth, Charitepl1, D-10117 Berlin, Germany

来源：

COMPUTERS IN BIOLOGY AND MEDICINE | 2024年 / 168卷

基金：

欧盟地平线“2020”;

关键词：

Mandibular reconstruction; Fibula free flap; CAD/CAM; Titanium; Magnesium; Finite element; Mechanobiology; MECHANO-REGULATION; IMPLANTS; PLATES; STRESS;

D O I：

10.1016/j.compbiomed.2023.107817

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Titanium patient-specific (CAD/CAM) plates are frequently used in mandibular reconstruction. However, tita-nium is a very stiff, non-degradable material which also induces artifacts in the imaging. Although magnesium has been proposed as a potential material alternative, the biomechanical conditions in the reconstructed mandible under magnesium CAD/CAM plate fixation are unknown. This study aimed to evaluate the primary fixation stability and potential of magnesium CAD/CAM miniplates. The biomechanical environment in a one segmental mandibular reconstruction with fibula free flap induced by a combination of a short posterior titanium CAD/CAM reconstruction plate and two anterior CAD/CAM miniplates of titanium and/or magnesium was evaluated, using computer modeling approaches. Output parameters were the strains in the healing regions and the stresses in the plates. Mechanical strains increased locally under magnesium fixation. Two plate-protective constellations for magnesium plates were identified: (1) pairing one magnesium miniplate with a parallel titanium miniplate and (2) pairing anterior magnesium miniplates with a posterior titanium reconstruction plate. Due to their degradability and reduced stiffness in comparison to titanium, magnesium plates could be beneficial for bone healing. Magnesium miniplates can be paired with titanium plates to ensure a non-occurrence of plate failure.

引用

页数：9