Modelling systemic risk factors in cardiovascular disease using single-cell biology

被引：0
|
作者：
Monaco, Claudia [1 ]
Dib, Lea [1 ]
机构：
[1] Univ Oxford, Kennedy Inst, Oxford, England
来源：
NATURE CARDIOVASCULAR RESEARCH | 2023年 / 2卷 / 06期
关键词：
RHEUMATOID-ARTHRITIS; INFLAMMATION; COLCHICINE; TRIAL;
D O I：
10.1038/s44161-023-00285-z
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The plasma of individuals with atherosclerosis contains cytokines that induce a pathogenic signaling cascade in immune cells. Saracatinib, a dual kinase inhibitor that targets the tyrosine kinases SRC and BCR-ABL, can prevent activation of this phospho-signaling pathway implicated in the pathogenesis of cardiovascular disease.
引用
收藏
页码：496 / 497
页数：2
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